Phase Separation Is an Evolvable Trait, Argues New Evolutionary Framework
A new perspective argues that liquid–liquid phase separation should be studied as an evolvable molecular phenotype shaped by natural selection.
Tag: liquid-liquid phase separation
Crowded molecular environments steer synthetic DNA droplet self-assembly
Macromolecular crowding with polymers such as PEG promoted the formation of synthetic DNA nanostar droplets and allowed researchers to control ...
RNA-Binding Protein VCX3A Drives Spermatogonial Cell Proliferation and Motility Through Splicing Control
A new Cell & Bioscience study shows that the RNA-binding protein VCX3A cooperates with the splicing regulator KHDRBS1 to promote ...
Phase-Separating Condensates Emerge as Drivers of Glioblastoma Progression and Drug Resistance
A review in Acta Neuropathologica Communications describes how aberrant liquid-liquid phase separation may drive glioblastoma progression and therapy resistance, and ...
New Study Identifies UBA1 as a Key Biomarker in Multiple Myeloma
A new study identifies UBA1 as a primary candidate biomarker for multiple myeloma by integrating ubiquitination and liquid-liquid phase separation ...
Tiny Droplets Inside Cells Could Decide Whether Cancer Therapy Works
A new review in Molecular Cancer synthesizes how liquid-liquid phase separation shapes radiosensitivity, immune evasion, and treatment resistance in cancer.
Physicists Map the Invisible Forces That Fold the Human Genome Inside the Nucleus
A new opinion article explains how phase separation, loop extrusion, and nuclear membrane adsorption together shape the 3D folding of ...
How Molecular Flux and Rigid β Motifs Drive Fibril Growth at Condensate Interfaces
New simulations reveal that rigid β-prone motifs and the rate of molecular delivery jointly determine whether aging condensate interfaces spread ...
Mutations Give RNA Droplets Their Own Genes, Vacuoles and Movement
Researchers have shown that RNA droplets trap their own DNA templates, and that even low rates of mutation produce stable ...
Phase-Separation Discovery Reveals How a Key Gene-Regulating Complex Assembles Itself
New research shows that the scaffolding protein KANSL1 forms liquid-like condensates that assemble the NSL chromatin complex and drive the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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