Phase-Separation Discovery Reveals How a Key Gene-Regulating Complex Assembles Itself
New research shows that the scaffolding protein KANSL1 forms liquid-like condensates that assemble the NSL chromatin complex and drive the ...
Tag: liquid-liquid phase separation
Stress-Triggered SMN Droplets Act as a Rescue System for Misplaced Splicing Machinery
Researchers in Bonn have discovered that the SMN protein forms reversible cytoplasmic condensates under stress to trap and clear misplaced ...
Why Supersaturating Drug Formulations Fail: A Unified Look at Cocrystals, Dispersions and Co-Amorphous Systems
A new review argues that the success of supersaturating drug delivery systems depends on controlling the kinetics of supersaturation generation, ...
How Liquid Droplets Inside Cells May Drive Cancer—and What Drugs Could Do About It
A new review in Molecular Cancer provides a rigorous framework for how liquid–liquid phase separation drives cancer biology and evaluates ...
Liquid Droplets Inside Cancer Cells Explain Why a Leukemia Drug Works So Slowly
A new Cell Research study shows that BCR-ABL1 forms liquid-like phase-separated condensates inside leukemic cells that physically slow tyrosine kinase ...
Liquid Droplets Inside Cells Emerge as Promising New Targets for Cancer Therapy
A new review details how dysregulated liquid–liquid phase separation drives cancer and how engineered peptides, modification mimics and synthetic condensates ...
PhaseOM Unifies Phase-Separation Analysis and Key-Residue Detection in One Framework
Liquid–liquid phase separation, the process by which molecules spontaneously condense into concentrated droplets without a surrounding membrane, has become one ...
Phase Separation Shapes Cell Membranes and Condensates
In the intricate world within living cells, the principle of phase separation emerges as a vital mechanism that orchestrates the ...
Rapid Discovery of Cellular Biomolecular Condensates and Proteins
In the ever-evolving field of cell biology, the ability to identify and understand biomolecular condensates has become paramount. These structures, ...
Biomolecular Condensates in Pro-β-Carboxysome Assembly
In the intricate world of cellular biology, the assembly of biomolecular structures often reveals astonishing mechanisms that sustain life at ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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