Tag: lipid nanoparticles

A new mRNA vaccine strategy called Proactive Immune Training primes the immune system with one antigen and boosts it with ...

A modular threaded microneedle system delivers a senescence-fighting hydrogel to the dermis and metabolism-restoring mRNA nanoparticles to subcutaneous fat, reversing ...

A new review in the Journal of Pharmaceutical Investigation details how targeted, stimuli-responsive, and immune-modulating nanocarriers could overcome lung barriers ...

A new review in Advanced Science maps how in vivo direct reprogramming converts resident cells into functional replacements for damaged ...

Researchers found that the natural nucleotide CMP dramatically amplifies floxuridine-driven cGAS–STING antitumor immunity and packaged the pair into nanoparticles that ...

A new review details how mRNA therapeutics are expanding beyond infectious disease vaccines into cancer immunotherapy, protein replacement, autoimmune tolerance, ...

A microfluidic technique that arranges metabolic and therapeutic RNAs in defined layers inside lipid nanoparticles raises ATP levels, boosts translation, ...

A new review argues that pharmacokinetic modeling frameworks such as PBPK, PopPK, and the proposed MIND workflow can bridge the ...

A new Nature Reviews Bioengineering review details how machine learning is transforming nanoparticle drug delivery design, from formulation optimization and ...

A new review outlines how aptamer-guided nanocarriers could finally deliver CRISPR-Cas9 gene editing specifically to tumor cells, integrating molecular targeting, ...