Computational Framework Ranks Safer RNA-LNP Formulations Before the Lab
Researchers at the University of Catania have built a modular computational framework that ranks RNA-lipid nanoparticle formulations for safety and ...
Tag: lipid nanoparticles
Rethinking Cancer Vaccine Carriers: A Bottleneck-First Test of Antigen Delivery Platforms
A new review in Materials Today Bio proposes a bottleneck-first framework for evaluating antigen delivery platforms in therapeutic cancer vaccines, ...
Camouflaged Nanoparticles Could Rewrite the Rules of Cancer Vaccines
A new review details how nanoparticles disguised with red blood cell membranes, exosomes, and synthetic coatings, loaded with personalized neoantigens, ...
Lipid Nanoparticle CAR Engineering Reveals Synergy Between T Cells and Macrophages Against Leukemia
A new study shows that lipid nanoparticle-delivered CAR mRNA engineers both human T cells and macrophages against CD19-positive leukemia cells, ...
Cancer Vaccines Enter a New Era as Personalized Immunotherapy Gains Momentum
A new review charts how mRNA, peptide, cell, and virus-based therapeutic vaccines, supercharged by AI-driven neoantigen prediction and combination immunotherapy, ...
Green Solvents Made From Natural Ingredients Could Transform Drug Delivery
A new review in the Journal of Nanoparticle Research details how natural deep eutectic solvents integrated into nanocarriers could deliver ...
Bigger Cargo, Better Design: Lipid Nanoparticles Rethought for Giant Gene Editors
A new Nature Biotechnology study shows that screening ionizable lipids with gene-editor-sized RNA cargo identified LC-1, a lipid nanoparticle formulation ...
New Lipid Nanoparticles Supercharge CRISPR Delivery of Bulky Gene-Editing RNA
Researchers at the University of Toronto engineered an ionizable lipid, LC-1, that preserves its fusogenic structure when loaded with large ...
AI framework designs mRNA vaccines that survive months without refrigeration
An AI framework called AGENT has engineered solid-state mRNA vaccines that retain full bioactivity after two months at 37 degrees ...
AI-Guided Design Yields mRNA Vaccines That Survive Months Without Refrigeration
MIT researchers used a data-efficient AI framework to discover solid-state mRNA–lipid nanoparticle vaccine formulations that retained full bioactivity after months ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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