Lipid Nanoparticles Trigger Pain Receptor TRPA1 and Reshape Calcium Signaling in Cells
New research shows that synthetic lipid nanoparticles trigger irregular calcium signals in cells partly through the pain-sensing ion channel TRPA1, ...
Tag: lipid nanoparticles
Where mRNA Vaccines Really Go: New Review Maps the Journey of Lipid Nanoparticles Through the Body
A new review synthesizes preclinical and clinical evidence showing that lipid nanoparticle biodistribution, mRNA persistence, and protein expression are distinct ...
Particle Engineering Takes Center Stage as Pharma Formulation Science Pushes Toward the Clinic
The Journal of Pharmaceutical Investigation has announced a January 2027 special issue, with submissions due June 30, 2026, dedicated to ...
Engineered Macrophages Emerge as a New Frontier in Cell Therapy for Solid Tumors
A new review details how chimeric antigen receptor-engineered macrophages are overcoming the barriers that stalled CAR-T therapy in solid tumors, ...
SPP1 emerges as a master switch shaping the tumor immune landscape
A new review details how the matrix protein SPP1 orchestrates immunosuppression across the tumor microenvironment and outlines emerging strategies to ...
Nanoparticle Geometry Boosts Antibiotic Power Against MRSA
Scientists have shown that tuning the internal nanoscale curvature of lipid nanoparticles can dramatically enhance the antibiotic daptomycin's ability to ...
Lactate Fuels a Deadly Feedback Loop That Drives Gut Damage in Ulcerative Colitis
A new study in Genome Medicine reveals that lactate produced by inflamed gut cells fuels an ACSS2-driven histone lactylation feedback ...
Lipid Nanoparticles Deliver CAR Instructions to T Cells Without Viruses
Researchers have engineered a custom ionizable lipid nanoparticle that delivers CAR-encoding mRNA into human T cells with over 90 percent ...
mRNA Vaccine Paired With Radiotherapy Shrinks HER2-Positive Lung Tumors in Mice
A HER2-targeted mRNA lipid nanoparticle vaccine combined with fractionated radiotherapy suppressed tumor growth and reprogrammed the immune microenvironment in a ...
SUNY Invests $400,000 in Quantum Sensors, AI Cancer Diagnostics and Burn-Scanning Tech
SUNY Chancellor John B. King Jr. has announced $400,000 in Technology Accelerator Fund seed grants supporting nine faculty-led projects ranging ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!