Charge-Switching Lipids Make Lipid Nanoparticles Safer for Gene Delivery
Newly developed charge-switching S-lipids keep lipid nanoparticles neutral in circulation but cationic inside acidic endosomes, enabling nucleic acid delivery with ...
Tag: lipid nanoparticles
Densely Modified RNA Guides Push Prime Editing to Nearly 70% Efficiency in Living Mice
Scientists have engineered densely chemically modified guide RNAs that boost prime editing efficiency in the mouse liver to nearly 70 ...
Smart Nanoparticles Reprogram Tumour Defenses to Boost Immune Attack on Cancer
Adelaide University researchers have developed mRNA lipid nanoparticles that reprogram immunosuppressive tumour-associated macrophages to recruit cancer-fighting T cells, showing reduced ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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