Glycolysis enzymes emerge as central players in Alzheimer’s brain energy failure
A new review argues that dysregulated glycolytic and pyruvate-metabolizing enzymes in specific brain cell types form a central axis linking ...
Tag: lactate
Why Lactate Infusions Trigger Panic but Hard Exercise Rarely Does
A new review argues that neither lactate's origin nor its blood concentration explains why infusions provoke panic while exercise rarely ...
Apigenin boosts norepinephrine release and brain lactate in aging-model mice
A new mouse and cell study found that the plant flavonoid apigenin improved chemically induced cognitive deficits by activating GPR30 ...
Lactate Drives Immune Evasion in Pancreatic Cancer via TRMT6-SIRT5 Axis
A new study reports that lactate in the pancreatic tumor microenvironment promotes metabolic reprogramming and PD-L1 upregulation through the TRMT6-SIRT5 ...
Cerebrospinal Fluid Analysis: From Lumbar Puncture Technique to Clinical Biomarker Interpretation
A new narrative review maps how cerebrospinal fluid physiology, lumbar puncture technique, and phase-based biomarker interpretation underpin neurological diagnosis.
Sepsis Resuscitation Shifts Focus to Tissue Perfusion Over Fluid Rules
A new commentary argues that early sepsis care should target tissue perfusion directly, since large trials show neither early vasopressors ...
In vivo isotope tracing maps fat-making flux in KRAS lung tumors and host tissues
In vivo isotope tracing in KRAS-driven lung cancer mouse models shows that tumor fat synthesis draws mainly on lactate and ...
Glycolysis Metabolites Linked to Short-Term Mortality After Heart Attack
A study of 724 STEMI patients found that elevated glucose, lactate, pyruvate and citrate were each significantly associated with death ...
Blood gas readings at the emergency door flag who is most likely to die
A retrospective German cohort study finds that anemia, acidosis and low bicarbonate on initial point-of-care blood gas analysis were independently ...
Exercise-linked lactate may remodel the post-stroke brain through tubulin modification
A new review argues that lactate released during aerobic exercise could modify the neuronal protein α-tubulin and support neural remodeling ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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