Rising Lactate Levels May Signal Deadly Neonatal Bowel Disease Early
A retrospective study used group-based trajectory modeling to show that a steeply rising lactate pattern in neonates with necrotizing enterocolitis ...
Tag: lactate
Lactate Fuels a Deadly Feedback Loop That Drives Gut Damage in Ulcerative Colitis
A new study in Genome Medicine reveals that lactate produced by inflamed gut cells fuels an ACSS2-driven histone lactylation feedback ...
Lifting Weights May Rejuvenate the Aging Brain’s Metabolism and Deepen Sleep
A randomized trial in GeroScience found that twelve weeks of explosive resistance training lowered resting lactate in the sensorimotor cortex ...
Sugar Metabolism Emerges as a Master Switch Controlling Bone Rebuilding
A new review argues that glycolysis acts as a signaling hub in bone remodeling, with glycolytic enzymes and metabolites such ...
Lactate Tag on Histones Fuels Drug Resistance in Head and Neck Cancer
New research shows that CBP-driven histone H3K18 lactylation activates GLI2 transcription, promoting head and neck squamous cell carcinoma progression and ...
Lactate’s Hidden Switch: How a Once-Dismissed Metabolite Shapes Brain Repair and Degeneration
A new review in the Journal of Translational Medicine details how lactate and protein lactylation act as a double-edged sword, ...
c-MET Signaling Reshapes the Lung Cancer Immune Landscape in Space and Metabolism
A new review in the Journal of Translational Medicine argues that c-MET signaling shapes spatially confined, metabolically driven immunosuppressive niches ...
Blood Metabolites Emerge as Powerful New Signals for Predicting Cancer Outcomes
A new review maps how advances in plasma metabolomics detection technology are turning tumor-driven metabolic fingerprints in blood into tools ...
Single-Cell Atlas Reveals How the Metabolic Enzyme PDK4 Drives Scarring After Heart Attack
A single-cell atlas of nearly a quarter-million cardiac fibroblasts reveals eight distinct cell populations and identifies the metabolic enzyme PDK4 ...
Sun-Powered Microbes Turn CO2 Into Industrial Organic Acids
A new review details how engineered cyanobacteria are being transformed into photosynthetic cell factories that convert carbon dioxide and sunlight ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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