Lactate Rewrites the Epigenome to Tear Down the Retina’s Protective Barrier in Diabetes
New research reveals that lactate-driven histone H3K9 lactylation activates a PTK2–FMNL2 signaling axis that breaks down the retinal endothelial barrier ...
Tag: lactate
Glycolytic Enzyme Accelerates ALS by Fueling Inflammatory Neuron Death
New research shows that loss of TDP-43 in ALS drives the glycolytic enzyme ALDOA to trigger inflammatory pyroptotic death of ...
Lactate Overload Blocks Kidney Recovery by Crippling Mitochondria Through MRS2
A new study shows that lactate accumulating during reperfusion drives maladaptive metabolic reprogramming in acute kidney injury by triggering MRS2-dependent ...
Why Vacuum-Packaged Beef Turns Brown Remains a Meat Science Mystery
A study of discolored vacuum-packaged beef found increased metmyoglobin and lactate but no single antioxidant, metabolic or pH-related cause.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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