Phase Separation Is an Evolvable Trait, Argues New Evolutionary Framework
A new perspective argues that liquid–liquid phase separation should be studied as an evolvable molecular phenotype shaped by natural selection.
Tag: intrinsically disordered regions
New open platform links molecular simulations to NMR data across the GPCRome
An open platform called GPCRmd-NMR combines molecular dynamics simulations with NMR spectroscopy to expose hidden conformational dynamics across more than ...
Machine Learning Reads Protein Disorder to Sort Autism Genes from the Rest
A new machine learning study shows that the amount of intrinsic disorder in a gene's protein product can help distinguish ...
Plants Build Their Own Sunscreen From Protein Condensates Under Intense Light
A Nature Plants highlight describes how singlet oxygen triggers MBS1 protein condensates that shield chloroplasts from excess light, and how ...
Phase-Separation Discovery Reveals How a Key Gene-Regulating Complex Assembles Itself
New research shows that the scaffolding protein KANSL1 forms liquid-like condensates that assemble the NSL chromatin complex and drive the ...
How Liquid Droplets Inside Cells May Drive Cancer—and What Drugs Could Do About It
A new review in Molecular Cancer provides a rigorous framework for how liquid–liquid phase separation drives cancer biology and evaluates ...
Unraveling Protein-RNA Interactions: The Dual Role of Zinc Fingers and Disordered Regions
In a groundbreaking study from the Institute of Science Tokyo, researchers have unveiled the sophisticated dual-binding mechanism employed by the ...
Nuclear SREBP2 Condensates Control Lipid Gene Activation
In a groundbreaking advance poised to reshape our understanding of cholesterol regulation, a recent study elucidates the molecular orchestration behind ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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