Mapping STING Mutations to Unlock Immunity and New Therapies
A comprehensive atlas of STING mutations consolidates genetic, structural, and clinical data to clarify how variants drive autoinflammation, immunodeficiency, and ...
Tag: interferon signaling
Where does the immune pressure go? New framework explains immunotherapy resistance
A new Molecular Cancer review proposes immune-pressure redistribution as a unifying framework explaining why patients resist PD-1/PD-L1 blockade and how ...
New Single-Cell Framework Maps How Myeloid Cells Shape Cancer Immunity
Researchers have built an open-source single-cell framework that maps injury, resolution and antigen-presentation programs in tumor myeloid cells across cancers.
Long Noncoding RNAs Emerge as a Shared Language Between Hosts and Pathogens
A Cell Research commentary highlights how long noncoding RNAs mediate regulatory communication between hosts and pathogens across kingdoms, reshaping infection ...
Hidden RNA Regulators Uncovered in Antiphospholipid Syndrome Blood Cells
A cross-dataset transcriptomic analysis has identified twenty-four candidate dysregulated long non-coding RNAs in antiphospholipid syndrome neutrophils and mapped a predicted ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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