Tag: interferon signaling

A new Frontiers in Lupus Research Topic shows that cardiovascular risk in systemic lupus erythematosus arises from a complex interplay ...

A new review in the Journal of Translational Medicine proposes that the physical mechanics of solid tumors govern whether mitochondrial ...

Single-cell sequencing of blood samples taken before and after liver transplantation reveals immune signatures that predict which patients will suffer ...

Xiamen University researchers report that inhibiting RNASET2, a magnesium-sensitive enzyme that clears mitochondrial double-stranded RNA, ignites innate immune signaling in ...

A new review maps how organoid and organ-on-a-chip platforms can reconstruct the microenvironmental logic of systemic sclerosis, lupus, and rheumatoid ...

New research links LINE-1 retrotransposon overexpression and homologous recombination deficiency in gastric cancer to heightened immune pathway activation and potential ...

In vivo CRISPR screens reveal that the epigenetic enzyme DNMT3A can both preserve and suppress tumor immune visibility, reshaping how ...

A comprehensive atlas of STING mutations consolidates genetic, structural, and clinical data to clarify how variants drive autoinflammation, immunodeficiency, and ...

A new Molecular Cancer review proposes immune-pressure redistribution as a unifying framework explaining why patients resist PD-1/PD-L1 blockade and how ...

Researchers have built an open-source single-cell framework that maps injury, resolution and antigen-presentation programs in tumor myeloid cells across cancers.