Tag: interferon signaling

A computational transcriptomic analysis demonstrates that sex differences in metabolic liver disease are defined by pathway architecture and continuous severity ...

A narrative review in Frontiers in Medicine finds artificial intelligence tools for cutaneous lupus erythematosus remain investigational, showing early promise ...

A study in rhesus macaques demonstrates that transient treatment with envelope-specific antibodies during antiretroviral therapy fosters sustained viral control after ...

A retrospective study in clear cell renal cell carcinoma identified an archival-compatible three-gene onco-immune score associated with worse overall survival ...

Promoter hypermethylation suppresses the long non-coding RNA HAND2-AS1 in bladder cancer, while experimental restoration inhibits tumor growth and activates interferon-related ...

A scientific review details how the ACOD1-itaconate immunometabolic axis alters cellular metabolism to govern inflammation, antimicrobial defense, and context-dependent tumor ...

A scientific review outlines how copper-induced mitochondrial proteotoxicity could trigger innate immune sensing to counteract immunosuppressive microenvironments in glioblastoma.

A commentary in EMBO Molecular Medicine reviews lysine pyruvylation, a protein modification that links pyruvate metabolism to immune signaling and ...

Researchers have demonstrated that the transmembrane protein CMTM6 maintains hematopoietic stem cell homeostasis in mice by preventing the lysosomal degradation ...

Pre-treatment gene signatures combining immune activity and tumor-intrinsic markers such as SLC7A5 and SOX2 are associated with response and resistance ...