Head-to-head comparison of two interferon-gamma tests for tuberculosis infection
A large real-world study comparing QuantiFERON-TB Gold Plus and T-SPOT.TB across more than 7,000 samples reveals fair agreement between the ...
Tag: interferon-gamma
Simple Blood Test May Predict Success of NK Cell Immunotherapy in Breast Cancer
A new study links baseline IFN-γ-based NK cell activity to ex vivo expansion capacity of autologous NK cells, offering a ...
Bladder Cancer Protein GSDMB Boosts Immunotherapy by Recruiting Immune Cells
A new study reveals that the protein GSDMB enhances anti-PD-1 immunotherapy in bladder cancer by driving Sema7a-mediated recruitment and activation ...
Same Immune Cells That Guard Against Disease Also Block Tissue Regeneration
New research shows CD4+ T cells kill the progenitor cells needed to rebuild bone after injury, while regulatory T cells ...
Human 3D Tumor Assembloids Reveal How Targeted Interferon-Gamma Therapies Could Outsmart the Tumor Microenvironment
Roche researchers validate a human 3D immune-containing colorectal cancer assembloid platform that captures interferon-gamma signaling, uncovers fibroblast plasticity, and demonstrates ...
Scientists Use Immune Informatics to Sketch a First Vaccine Blueprint Against Human Metapneumovirus
A computational reverse vaccinology study has designed BAFF- and APRIL-adjuvanted multi-epitope vaccine candidates against human metapneumovirus, a major respiratory pathogen ...
Blocking FGFR Signaling Supercharges Immunotherapy in Hard-to-Treat Colorectal Cancer
New research shows that inhibiting the FGFR signaling pathway reduces T cell exhaustion and repolarizes macrophages, significantly enhancing PD-1 blockade ...
Aging Blunts Non-Spike T Cell Defenses After COVID Vaccines and Breakthrough Infection
A longitudinal study finds that older adults who recovered from COVID-19 mount weakened non-spike-specific Th1 CD4+ T cell responses to ...
Hidden Immune Brake Found to Keep Gut Inflammation in Check
Researchers report that the transcription factor Zbtb44, through SUMOylation-dependent interaction with T-bet, represses interferon-gamma production by T cells and thereby ...
Gut microbes from schizophrenia patients trigger brain inflammation in mice
A new Translational Psychiatry study shows that gut microbiota transplanted from schizophrenia patients into healthy mice induces intestinal inflammation, Th17/Th1-skewed ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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