Tag: innate immunity

A reanalysis of chromatin data from human monocytes shows that Alu elements gain enhancer-associated histone marks during bacterial LPS stimulation, ...

A review in Frontiers in Pediatrics summarizes how the fetal adaptive and innate immune systems develop across gestation and how ...

A new review explains how neutrophil, complement, and barrier defects reshape antibiotic activity in immunocompromised patients with resistant bacterial infections.

Autophagy in alveolar macrophages restrains IL-1α production, and blocking it primes innate immunity that speeds clearance of bacterial and viral ...

A case-control study in Iraq finds markedly elevated LL-37 and TLR-9 levels in rheumatoid arthritis patients alongside pro-atherogenic lipid shifts ...

BET inhibition suppresses STING expression at its promoter and enhancer regions, weakening the immune response triggered by PARP inhibitors.

Researchers found that the immune sensor MDA5 moves to the cell surface during lung injury to clear extracellular RNA, and ...

A new review frames the cGAS-STING DNA-sensing pathway as a self-reinforcing inflammatory amplifier that links cellular damage to whole-joint remodeling ...

A bone marrow chimera study in mice shows that deleting the CLEC4E receptor in cardiac resident cells, rather than in ...

A new study in Myeloid Cells reports that the vaccine adjuvant AS01 induces trained immunity in human monocytes and slows ...