High EBV DNA in Children’s Blood Linked to Immune Imbalance and Secondary Infections
A transcriptomic study of 65 children links high plasma EBV-DNA load to innate immune hyperactivation, impaired adaptive immunity, and a ...
Tag: innate immunity
Snake Virus Study Reveals Hidden Immune Damage Behind a Deadly Reptile Disease
A comprehensive study of 133 boa constrictors shows that boid inclusion body disease selectively impairs phagocytic immune cells and lowers ...
Flu Virus Protein NS2 Sabotages Interferon Alarm by Hijacking Host Ubiquitin Regulator UBL7
New research shows that influenza A virus protein NS2 suppresses type I interferon signaling by competing with MAVS to bind ...
Designed Protein Blocks Inflammation Receptor at Its Membrane Core
Scripps Research scientists used computer-aided protein design to create a synthetic transmembrane protein that binds TLR4 inside the cell membrane ...
African swine fever virus reshapes host genome architecture within hours of infection
New research shows that African swine fever virus extensively reorganizes host chromatin architecture and RNA polymerase II activity within hours ...
Bitter Taste Receptor Gene Behaves the Same Across the Sinuses, Study Finds
A prospective study of 253 sinonasal biopsies shows that TAS2R38 bitter taste receptor gene expression in chronic rhinosinusitis varies between ...
Blocking a Magnesium-Sensing RNA Shredder Makes Cancer Immunotherapy Work Better
Xiamen University researchers report that inhibiting RNASET2, a magnesium-sensitive enzyme that clears mitochondrial double-stranded RNA, ignites innate immune signaling in ...
How Malaria Parasites Punch Through Cells to Spark Protective Immunity
New research shows that the damage malaria sporozoites inflict while punching through host cells, sensed via a wounding response requiring ...
Viral Saboteur Unmasked: How EBV Silences a Key Immune Molecule to Drive Nasopharyngeal Cancer
A new review in Cancer Immunology, Immunotherapy details how EBV-encoded miR-BART4 suppresses the innate immune molecule BPIFB1/LPLUNC1, whose loss promotes ...
SARS-CoV-2 Enzyme NSP14 Disrupts DHX15-RIG-I Partnership to Silence Antiviral Alarm
New research shows that the SARS-CoV-2 enzyme NSP14 suppresses interferon production by binding the helicase DHX15 and disrupting its cooperative ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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