cGAS-STING DNA Sensing Emerges as a Central Amplifier of Osteoarthritis
A new review frames the cGAS-STING DNA-sensing pathway as a self-reinforcing inflammatory amplifier that links cellular damage to whole-joint remodeling ...
Tag: inflammation
Vagus nerve stimulation may curb inflammation by controlling HMGB1 access to cells
A new perspective proposes that vagus nerve stimulation may curb inflammation and pain by limiting the release and cellular uptake ...
How Farm Air Pollution May Reach the Gut and Drive Metabolic Disease
A new review synthesizes evidence that inhaled agricultural particulate matter may disrupt the intestinal barrier and gut microbiome through the ...
Circular RNA Shows Protective Signals in Mouse and Cell Models of Sepsis-Linked Kidney Injury
A new study reports that circ_0000745 attenuated renal and cellular injury endpoints in mouse and cell models of sepsis-induced acute ...
Palmitoylation Enzyme ZDHHC5 Emerges as Driver of Neutrophil Inflammation in COPD
A new study links the palmitoyltransferase ZDHHC5 and its modification of NOD2 to neutrophil extracellular trap formation, mitophagy and lung ...
HSP90B1 drives cardiomyocyte pyroptosis and inflammation after heart attack, mouse study finds
A new study links the ER chaperone HSP90B1 to cardiomyocyte pyroptosis, NF-κB/NLRP3 signaling, and M1-like macrophage polarization after myocardial infarction.
Mutated neutrophils may trigger immune self-attack in lupus patients
New research in Nature finds that 33 of 34 lupus patients carried neutrophils with RNA splicing mutations producing neoantigens that ...
Serum microRNA miR-1287-5p emerges as a candidate biomarker and driver of knee osteoarthritis
A single-centre study found serum miR-1287-5p elevated in knee osteoarthritis patients and showed in chondrocyte experiments that the microRNA promotes ...
Journal Retracts 2018 Valproic Acid Brain Injury Study Over Image Integrity Concerns
Frontiers in Molecular Neuroscience has retracted a 2018 study on valproic acid and traumatic brain injury after an investigation found ...
Exercise Trial Tests Whether Training Boosts Fitness and Immune Markers After Kidney Transplant
The EXTRA Trial will test whether 24 weeks of supervised aerobic and resistance training improves fitness, immune markers, and graft-related ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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