Gut Metabolite Genes Could Predict Colorectal Cancer Survival and Immunotherapy Response
Researchers built a four-gene signature based on propionate metabolism that stratifies colorectal cancer patients by survival risk and links tumor ...
Tag: Immunotherapy
Engineered Immune Cells Move From Cancer Care Toward the Clinic Against Infections
A new review in the Journal of Translational Medicine charts how CAR-T-cell technology is being adapted from cancer treatment to ...
Two-Pronged Immunotherapy Strategy Cracks Glioblastoma’s Defenses in Preclinical Study
Wistar Institute scientists report that combining the kidney cancer drug axitinib with a 4-1BB agonist overcame myeloid cell suppression and ...
AI-Designed Protein Binders Face Real-World Test in Landmark CAR T Cell Competition
A crowdsourced competition called Bits to Binders tested 12,000 AI-designed minibinders as CAR T cell recognition domains, revealing both the ...
Under the Microscope: Tumor Invasion Grading Predicts Survival After Liver Cancer Conversion Therapy
A multicenter study shows that grading the severity of microvascular invasion in resected liver tumors strongly predicts recurrence and survival ...
New 3D Fluorescence Imaging Technique Maps PD-L1 in Lung Cancer to Gauge Immunotherapy Response
An exploratory study in BMC Medicine presents a three-dimensional NIR-II fluorescence molecular tomography system fused with X-ray CT that quantifies ...
Flu Followed by Pneumococcal Pneumonia: A Multiple Sclerosis Case Exposes Gaps in Vaccine and Blood Monitoring
A Journal of Neurology case report describes severe invasive pneumococcal pneumonia after influenza A in a multiple sclerosis patient treated ...
Radiotherapy Still Matters in dMMR Endometrial Cancer, Researchers Warn in the Immunotherapy Era
A new Viewpoint in eClinicalMedicine argues that immune checkpoint inhibitors have not yet proven they can replace pelvic radiotherapy in ...
Scientists Uncover Why Esophageal Cancer Shrugs Off PD-1 Blockade
A new study shows that the protein SIRPĪ±, produced by esophageal cancer cells themselves, fuels both tumor growth and T-cell ...
New Antibody Targets BAMBI to Rewire Immune Cells in Psoriatic Arthritis
Spanish researchers have developed a humanized monoclonal antibody, hB101.37, that inhibits the BAMBI pseudoreceptor and rebalances T cell immunity, showing ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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