New Antibody Targets BAMBI to Rewire Immune Cells in Psoriatic Arthritis
Spanish researchers have developed a humanized monoclonal antibody, hB101.37, that inhibits the BAMBI pseudoreceptor and rebalances T cell immunity, showing ...
Tag: Immunotherapy
Myasthenia Gravis Strikes Hardest After 65, But Long-Term Outlook May Surprise
A new systematic review and meta-analysis finds that myasthenia gravis beginning at age 65 or older carries more than double ...
Indirect Trial Comparison Suggests Retifanlimab Edges Out Avelumab in Metastatic Merkel Cell Carcinoma
A matching-adjusted indirect comparison of two landmark trials suggests retifanlimab significantly prolongs progression-free survival compared with avelumab in metastatic Merkel ...
Exercise Emerges as a Serious Candidate Therapy in Cancer Prevention and Treatment
A new Nature Reviews Clinical Oncology review synthesizes epidemiological, trial and mechanistic evidence to argue that structured exercise is emerging ...
Blocking a Single Protein Makes Childhood Cancer Cells Easier for Immunotherapy to Find
Penn State researchers found that blocking the protein VPS34 raises levels of the GD2 molecule on neuroblastoma cells, making them ...
The Hidden Cost of Cancer Care: When Treatment Steals Patients’ Time
A new scoping review of 30 studies synthesizes the emerging evidence on time toxicity in cancer care, showing how treatment ...
Two Years of Ofatumumab Reshapes the Immune Landscape in Multiple Sclerosis
A two-year real-world study found that ofatumumab sustained B-cell depletion in multiple sclerosis patients while producing significant increases in broad ...
Lipid Nanoparticles Deliver CAR Instructions to T Cells Without Viruses
Researchers have engineered a custom ionizable lipid nanoparticle that delivers CAR-encoding mRNA into human T cells with over 90 percent ...
Nanovaccine Built From Metal–Organic Frameworks Drives Tumours Into Full Retreat
A metal–organic framework nanovaccine co-delivering tumour antigens and STING agonists induced systemic tumour regression, immune memory and synergy with radiotherapy ...
Why the Mouth Matters: Dentists Join the CAR-T Therapy Team
Hematologists argue that preventive dental care and oral health assessment should become a standard part of the CAR-T cell therapy ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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