Chromatin Regulator ANKRD11 Emerges as Switch That Reinvigorates Exhausted T Cells
Researchers have identified ANKRD11 as a chromatin regulator whose loss reprograms CD8+ T cells to fight chronic hepatitis B and ...
Tag: Immunotherapy
Pericyte-like cells may help shape the immune landscape of glioblastoma
New research shows that FAP-positive pericyte-like cells in glioblastoma promote the differentiation of monocytes into immunosuppressive tumor-associated macrophages.
Blood Proteins May Reveal Who Benefits Most From Lung Cancer Immunotherapy
The prospective SARC-LUNG study links circulating immunometabolic biomarkers such as sRAGE and FGF21 with survival and immune microenvironment profiles in ...
Japanese Gastric Cancer Care Transformed by Immunotherapy Shift, 12-Year Data Show
A 12-year Japanese database study of 16,573 patients shows first-line nivolumab plus chemotherapy rapidly displaced cisplatin-based regimens in HER2-negative advanced ...
Radiation After Liver Cancer Surgery Tops Rankings in Global Therapy Analysis
A network meta-analysis of 28 randomized trials finds that internal radiation and brachytherapy approaches, including iodine-125 brachytherapy, IMRT, and iodine-131-metuximab, ...
Self-Powered Nanogenerators Turn Body Motion Into a Weapon Against Cancer
A new review details how triboelectric nanogenerators that harvest the body's own mechanical energy could power cancer detection, drug delivery ...
How a Single Chemokine Can Sabotage Radiotherapy and Shape the Immune Battlefield
A new review explains how radiation-induced CCL2/CCR2 signaling recruits immunosuppressive myeloid cells and remodels the tumor microenvironment, and why combining ...
Landmark Guideline Maps the Entire Journey of Anti-Cancer Drugs Through Clinical Research
A comprehensive new guideline synthesizes the full landscape of anti-cancer drug clinical research, from preclinical requirements and trial phases to ...
AI maps collagen highways and myeloid roadblocks that trap T cells in pancreatic cancer
A new computational platform reveals how collagen architecture and myeloid cells cooperate to trap therapeutic T cells in pancreatic tumors, ...
Nanoparticles Could Help Radiation Turn Cancer Immunity Into Durable Treatment
A perspective proposes programmable nano-immunoadjuvants to amplify and sustain the antitumor immune responses initiated by radiotherapy.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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