Lab-Grown Tumours and Digital Twins Bring Precision Therapy to Oesophageal Cancer
A new review maps the laboratory models—from organoids to humanised mice to computational pipelines—that could finally bring personalised treatment to ...
Tag: Immunotherapy
Scientists Discover CD55 Is the Hidden Switch That Powers Natural Killer Cells Against Cancer
New research shows that CD55 acts as a self-sufficient ignition switch for natural killer cell attack on tumors, and that ...
Young Scientists Map the Next Quarter-Century of Cancer Research
Six emerging cancer researchers outline in a Nature Reviews Cancer anniversary viewpoint the technologies and paradigms that will shape oncology ...
Galectin-9 Emerges as a Key Driver of Immune Evasion in Cervical Cancer Progression
A multi-omics study traces cervical carcinogenesis from normal tissue to invasive cancer and identifies galectin-9-driven immune evasion as a promising ...
Radiation or Surgery After Dual Immunotherapy Fails to Extend Survival in Metastatic Lung Cancer
The Phase III LONESTAR trial found that adding radiation or surgery after nivolumab plus ipilimumab did not improve survival in ...
Ibrutinib Triggers Matriptase to Preserve CD19 and Block Antigen Escape in B-Cell Malignancy
New research shows that the BTK inhibitor ibrutinib activates the protease matriptase in malignant B cells, preserving surface CD19 and ...
T Cells Can Wipe Out Tumors Without Ever Recognizing Them
New research shows that activating bystander T cells inside tumors triggers antigen-independent tumor killing through cytokines, nitric oxide and innate ...
Neutrophils in Cancer: The Immune Cells That Turn Traitors and Healers
A comprehensive new review reveals how neutrophils, the immune system's most abundant white blood cells, are co-opted by tumors to ...
Radium-223 Therapy Lowers PD-L1 in Prostate Cancer Bone Metastases, PET Study Shows
A prospective imaging study shows that radium-223 significantly reduces PD-L1 expression and depletes immune cells in prostate cancer bone metastases, ...
Fatigue During Immunotherapy Does Not Track With Fitness, Study Finds
A German study finds that cancer patients on immune checkpoint inhibitors report far more chronic fatigue and lower fitness than ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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