When Lung Cancer Changes Identity: Study Maps the Immune Shift Behind Drug Resistance
A paired genomic and transcriptomic study of 32 patients shows that EGFR-mutant lung adenocarcinoma transforms into an immunosuppressed yet immunologically ...
Tag: Immunotherapy
AI Shows Promise Against Stomach Cancer, But Most Tools Are Not Ready for the Clinic
A comprehensive review finds that while artificial intelligence shows striking performance in detecting, staging, and predicting gastric cancer outcomes, most ...
FDA Approves Atezolizumab for Stage III dMMR Colon Cancer After Landmark ATOMIC Trial
The FDA has approved atezolizumab with chemotherapy for adjuvant treatment of stage III dMMR colon cancer after the phase III ...
Biomaterials That Talk to the Immune System Are Reshaping Immunotherapy
A new review maps how inorganic nanoparticles, polymers, DNA nanostructures, and cell-derived vesicles are being engineered to actively reprogram the ...
Fluid Once Discarded After Cancer Surgery Reveals a Hidden Immune Cell That May Shield Tumors
A Mass General Brigham study of malignant ascites has identified rare RORC-expressing dendritic cells that may promote immune tolerance in ...
Blood Test Clue: Immune Cells That Betray Early Lung Cancer Before It Strikes
Researchers have discovered a clonally coordinated network of suppressive regulatory T cells that spans the blood, lymph nodes and airways ...
How Pseudomonas aeruginosa Hijacks Protective T Cells to Fuel Cystic Fibrosis Lung Damage
New research shows Pseudomonas aeruginosa reprograms protective Th17 cells into pathogenic interferon-gamma-producing effectors that directly damage the cystic fibrosis lung ...
Ultrasound-Driven Bioactive Microrobots Deliver a Multi-Weapon Strike Against Bladder Cancer
An engineered ultrasound-responsive microrobot combining collagen-degrading bacteria, nanoparticles, and a targeted drug achieved strong tumor inhibition and immune activation in ...
Experimental Drug Tolinapant Boosts Immunotherapy Response in Advanced Solid Tumors
A phase I trial found that the IAP antagonist tolinapant combined with pembrolizumab was well tolerated and produced a 33 ...
Hidden Immune Saboteurs: Scientists Map the Cells That Shield Colorectal Tumors
By combining spatial and single-cell transcriptomics, researchers have mapped previously unknown immunosuppressive niches in colorectal cancer, including SPP1-positive macrophage rings ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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