DNA Repair Protein Fails to Explain Why a Common Dog Cancer Shrugs Off Chemotherapy Drug
New laboratory research shows that canine hemangiosarcoma cell lines resist the chemotherapy drug temozolomide through a mechanism independent of the ...
Tag: Immunotherapy
Nanoparticles That Clear Scar-Driving Immune Cells Open Tumors to Immunotherapy
Memorial Sloan Kettering scientists engineered fucoidan-coated nanoparticles that selectively eliminate senescent, P-selectin-positive macrophages driving fibrosis, dissolving scar barriers around tumors ...
Natural Killer Cells Take Center Stage in the Fight Against Liver Cancer
A comprehensive new review in Medical Oncology maps how natural killer cell therapies, from cytokine-expanded infusions to CAR-NK cells and ...
Insurance Paperwork Hits Nearly Half of Cancer Survivors, Study Finds
A survey of 459 long-term US cancer survivors found that nearly half reported insurance-related administrative burdens, which were linked to ...
How Tumor Metabolism Decides Whether Colorectal Cancer Immunotherapy Works
A new review in Cancer Cell International explains how metabolic reprogramming in colorectal cancer tumors suppresses anti-tumor immunity and how ...
Immune Cells Cluster, Not Crowd, in Melanoma That Spreads to the Brain
A Dutch study finds that melanoma brain metastases harbor far fewer but more tightly clustered immune cells than other metastases, ...
Radiomics Gives Doctors a Whole-Tumor Map Where Biopsies Only See a Point
A new review argues that radiomics should serve as a spatial context for biopsy-based biomarkers in head and neck cancer, ...
Chemoimmunotherapy Before Surgery Delivers Striking Survival Gains in Limited-Stage Small-Cell Lung Cancer
A retrospective real-world study found that neoadjuvant chemoimmunotherapy followed by surgery produced significantly longer overall survival and strong pathologic responses ...
Machine Learning Model Predicts Which Lung Cancer Patients Will Respond to Immunotherapy
Researchers developed a random forest model integrating six clinical, inflammatory and molecular predictors that forecasts immunotherapy response in advanced lung ...
Epigenetic Boost Fails to Awaken Immune Therapy in Bile Duct Cancer Trial
A phase 2 trial found that the HDAC inhibitor entinostat combined with nivolumab produced no tumor responses in advanced cholangiocarcinoma, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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