Nanoscale Imaging Reveals Protein Abundance Does Not Guarantee Antibody Access on Cancer Vesicles
High-speed atomic force microscopy reveals that antibody accessibility of PD-L1 on cancer-derived vesicles differs from protein abundance.
Tag: Immunotherapy
New Myasthenia Gravis Playbook Pairs Fast-Acting Antibody Blockers With Long-Term Immune Therapies
Seven real-world cases from a Greek neuromuscular center show how FcRn antagonists, rituximab and ravulizumab can be sequenced in generalized ...
Brazil’s CAR T-cell revolution: why a $500,000 cancer cure remains out of reach for most patients
The clinical case for expanding access to CAR T-cell therapy in Brazil rests on a substantial body of evidence demonstrating ...
Head-to-Head Comparison Reveals mRNA Vaccines Behave Differently in Human Blood
Australian researchers have completed the first head-to-head comparison of three mRNA-lipid nanoparticle vaccine platforms in human blood, revealing key differences ...
Hungary’s Decade of Data Reveals the Harsh Reality of Extensive-Stage Small Cell Lung Cancer
A nationwide analysis of 8,104 Hungarian patients treated from 2013 to 2022 shows median survival of just 9.3 months with ...
Microsatellite Instability Proves Rare but Stable Biomarker in Penile Cancer Study
A Brazilian study of 116 penile cancer patients found microsatellite instability in just 2.6 percent of cases but showed complete ...
Microglia-Mimicking Nanoparticles Deliver CO and GSDME to Fire Up Glioblastoma Immunotherapy
A biomimetic nanoplatform cloaked in microglial cell membranes delivers carbon monoxide, manganese ions, and Gasdermin E across the blood-brain barrier ...
New Python Package Puts Biomarker Discoveries to the Test Before They Reach the Clinic
A new open-source Python package called ROOFS benchmarks multiple feature selection methods on a researcher's own data, evaluating predictive performance ...
Immune Therapy’s Hidden Cost: Nearly Three in Ten Lung Cancer Patients Face Severe Financial Toxicity
A latent profile analysis of 331 lung cancer patients receiving immunotherapy identified three distinct financial toxicity groups, with lower income, ...
Blood Proteins Predict Who Responds to Cancer Immunotherapy, Pan-Cancer Review Finds
A comprehensive systematic review of 49 pre-treatment cohorts identifies circulating protein signatures, including inflammatory markers and T-cell activation ligands, that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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