Acellular Pertussis Vaccines Show Strong Early Protection but Waning Immunity
A narrative review synthesizes evidence on acellular pertussis vaccines across infants, children, adolescents, adults and pregnant women, reporting roughly 84–85% ...
Tag: immunogenicity
One-Week Intradermal Rabies Regimen Fails Equivalence Test Against Standard Schedule in Indian Trial
A phase 4 randomised trial in India found the one-week IPC intradermal rabies regimen did not meet prespecified equivalence with ...
Modelling Points to Ten Fixes for Better Phage Therapy
A new review outlines ten concrete measures, from phage selection to dosage modelling, for improving the consistency of phage therapy ...
Type II anti-CD20 antibody obinutuzumab outperforms rituximab in lupus trials, review finds
A new comparative review finds that the type II anti-CD20 antibody obinutuzumab succeeded in Phase 3 lupus trials where rituximab ...
Tildrakizumab Clears Skin in Most Indian Psoriasis Patients in Phase III Trial
A phase III single-arm trial found that 93.9 percent of Indian patients with moderate-to-severe plaque psoriasis achieved PASI 75 after ...
Engineered human AGO2 enables targeted C-to-U RNA editing in cells
Engineered human AGO2 and a C-to-U deaminase produced average messenger RNA editing 1.9-fold higher than two Cas13 comparators in HEK293T ...
Two Japanese Encephalitis Vaccines Can Be Safely Mixed, Landmark Indian Trial Finds
A phase 4 randomized trial across five Indian hospitals shows that the inactivated Japanese encephalitis vaccines JENVAC and JEEV can ...
COVID-19 Booster Debate: Why Heterologous Advantage May Be Overstated
A new letter in New Microbes and New Infections argues that pooled evidence favoring heterologous COVID-19 vaccine boosters is limited ...
Vaccine Responses Hold Up a Year After Stem Cell Transplants, Study Finds
A German study of 114 allogeneic stem cell transplant recipients shows that mRNA vaccination against SARS-CoV-2 is safe and largely ...
Biosimilar Trastuzumab EG12014 Matches Original Drug in Phase III Breast Cancer Trial
A Phase III trial of 807 patients found the trastuzumab biosimilar EG12014 statistically equivalent to reference trastuzumab in efficacy, safety, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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