Fluid Once Discarded After Cancer Surgery Reveals a Hidden Immune Cell That May Shield Tumors
A Mass General Brigham study of malignant ascites has identified rare RORC-expressing dendritic cells that may promote immune tolerance in ...
Tag: immune tolerance
Engineered Tolerance: Can CAR-Tregs Reset the Immune System in Vasculitis?
A new review in the Journal of Translational Medicine maps the evidence linking regulatory T cell dysfunction to vasculitis and ...
Nanozymes, Engineered Gut Bacteria and mRNA Offer New Hope Against Hyperuricemia
A sweeping review details how nanozyme cascade reactors, biomimetic delivery platforms, gut-targeted engineered probiotics, natural products, mRNA therapy and immune ...
Antibody Sugar Coatings Shift Within Weeks of Conception, Pregnancy Study Finds
A longitudinal study of 202 pregnancies shows that IgG and IgA glycosylation shift toward an anti-inflammatory profile as early as ...
Why Chronic Hepatitis B Still Defies a Functional Cure: New Review Maps the Immunological Barriers
A new review in Virology Journal explains how cccDNA persistence, viral genome integration and multi-level immune exhaustion keep functional cure ...
Blood Sugar Chains on Antibodies Forecast Dangerous Reactions to Allergy Shots
A new study shows that sugar structures on IgG antibodies in plasma change predictably during allergen immunotherapy and can predict ...
Liver Macrophages Carrying Apolipoprotein E Act as a Molecular Brake That Drives T Cell Exhaustion and Preserves Transplant Tolerance
A specialized APOE-producing Kupffer cell population in transplanted livers restrains rejection by driving attacking CD8-positive tissue-resident memory T cells into ...
Nanoplastics During Pregnancy Disrupt the Placenta by Skewing Immune Cells Toward Inflammation
New research shows that polystyrene nanoplastics impair placental function during pregnancy by suppressing the ARG1 gene and skewing macrophages toward ...
Harnessing T-Cell Exhaustion to Improve Organ Transplantation Outcomes
A new review in Genes & Diseases examines how T cell exhaustion may become both an obstacle and an opportunity ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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