African swine fever virus reshapes host genome architecture within hours of infection
New research shows that African swine fever virus extensively reorganizes host chromatin architecture and RNA polymerase II activity within hours ...
Tag: immune evasion
Cancer’s Hidden Helpers: Fibroblast Diversity Reshapes How Tumors Spread and How We Treat Them
A new review in Molecular Cancer maps the diverse states of cancer-associated fibroblasts and argues that precisely modulating, rather than ...
New Spatial Index Measures the Immune Barrier That Shields Tumours From Attack
Researchers have introduced the Spatial Immune Barrier Index, a spatial transcriptomics measure that quantifies the suppressive barrier holding immune cells ...
RNA Tagging Enzyme METTL16 Fuels Colorectal Cancer by Hijacking Amino Acid Metabolism and Silencing Immune Cells
New research shows that the RNA methyltransferase METTL16 drives colorectal cancer growth and immune evasion by stabilizing BCAT1 mRNA and ...
Collagen Receptor CD49b Emerges as Key Switch That Lets Breast Tumors Hide From Immunotherapy
Blocking the collagen receptor integrin alpha-2 (CD49b) on breast cancer cells remodels the tumor immune microenvironment and synergizes with anti-PD-L1 ...
SARS-CoV-2 Enzyme NSP14 Disrupts DHX15-RIG-I Partnership to Silence Antiviral Alarm
New research shows that the SARS-CoV-2 enzyme NSP14 suppresses interferon production by binding the helicase DHX15 and disrupting its cooperative ...
Fat Thieves: How Leishmania infantum Rewires Host Cell Lipids to Fuel Infection
New lipidomic research reveals how Leishmania infantum systematically drains and remodels host macrophage lipids to build its own biomass and ...
Chemical Tags on RNA Take Center Stage in Cancer’s Growth and Immune Evasion
A new review in Molecular Cancer details how the abundant RNA mark m6A drives cancer growth, immune evasion and treatment ...
Gene Signatures and Immune Suppression Mapped in Canine Lymphoma
RNA sequencing of canine diffuse large B-cell lymphoma has revealed a five-gene signature linked to survival trends and a tumor ...
Melanoma’s Genetic Blueprint Builds Immune-Proof Tumor Neighborhoods, Study Finds
Researchers at NYU Grossman School of Medicine show that loss of the NF1 tumor suppressor reorganizes melanoma tumors into immunosuppressive ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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