Cancer Cells Selectively Strip Gene-Rich Regions of the Y Chromosome to Fuel Tumor Growth
A new study shows that cancer cells selectively erode gene-rich regions of the Y chromosome, disrupting regulatory pathways and opening ...
Tag: immune evasion
Protein Glutamylation Emerges as a Versatile Signaling Mechanism Beyond the Cytoskeleton
A new review in Med Research redefines protein glutamylation as a versatile signaling-related post-translational modification with roles in immunity, development, ...
Lumpy Skin Disease Virus Suppresses Key Immune Genes in Cattle, Study Finds
A field study of naturally infected cattle in India reveals that lumpy skin disease virus broadly suppresses both Th1 and ...
DNA Damage Response Drives PD-L1 Shield That Lets Aging Cells Evade Immune Clearance
A new review proposes that the DNA damage response drives PD-L1 upregulation in senescent cells, enabling immune evasion and creating ...
Do Fungal Pathogens Exploit HLA-G-Mediated Immune Tolerance?
The distinction between classical and nonclassical major histocompatibility complex class I molecules helps explain why HLA-G occupies such a unique ...
AI Model Links Calcium Pump Gene ATP2A2 to Immune Evasion in Lung Cancer
A machine learning analysis of inflammation and metabolism genes across seven lung adenocarcinoma cohorts identifies the calcium pump gene ATP2A2 ...
Why the Immune System Fails Some Bladder Cancers and How Scientists Are Fighting Back
A new review explains why BCG immunotherapy fails in some bladder cancer patients and outlines emerging combination strategies designed to ...
Single-cell and bulk transcriptomic characterization of the osteosarcoma microenvironment reveals lineage-specific programs and inflammatory differences associated with metastasis
Osteosarcoma has long frustrated oncologists. It is the most common primary malignant bone tumor, striking hardest in adolescents, and while ...
How Emerging Viruses Cross Species Barriers: A Molecular Systems View of Replication, Immune Evasion and Precision Countermeasures
A new review synthesises molecular mechanisms of viral emergence across major virus families, arguing that receptor compatibility alone is insufficient ...
Ribosomal RNA Tag and a Detox Enzyme Form a Deadly Cancer Survival Circuit
A new review describes how the RNA methyltransferase METTL5 and the detox enzyme MGST1 form a signaling axis that helps ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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