MerTK links dexamethasone to weakened antiviral immunity in chronic LCMV infection
A mouse study found that MerTK largely mediated dexamethasone-associated suppression of antiviral CD8+ T cells and increased LCMV dissemination during ...
Tag: IL-10
Adult-sourced fecal microbiota transplantation ameliorates early-life antibiotic-induced intestinal immune stress in juvenile mice associated with the modulation of the TLR4/MyD88 signaling pathway
A controlled mouse study found that adult-sourced fecal microbiota transplantation after early-life antibiotics was associated with lower colonic TLR4 protein ...
Comparative study finds molecular differences in lupus-associated thrombocytopenia
A comparative study found differences in PVT1, miR-181a, RORγt, FOXP3 and circulating markers among patients with SLE-associated thrombocytopenia, patients with ...
Gut Microbiome Metabolite LysoPC(16:0) Drives Endometriosis via PPARγ and M2 Macrophage IL-10
Endometriosis, a chronic estrogen-dependent inflammatory disorder affecting more than 190 million women of reproductive age worldwide, has long frustrated researchers ...
Do Fungal Pathogens Exploit HLA-G-Mediated Immune Tolerance?
The distinction between classical and nonclassical major histocompatibility complex class I molecules helps explain why HLA-G occupies such a unique ...
Brain Immune Cells Nibble Away Parkinson’s Protein Clumps to Shield Vulnerable Neurons
University of Oxford researchers have discovered that a specialised population of human microglia protects dopamine neurons in Parkinson's disease by ...
Dead Probiotic Cells Show Promise for Healing Infected Burn Wounds in Mice
A new mouse study shows that non-viable probiotic cells, or paraprobiotics, can suppress bacterial virulence factors and shift infected burn ...
Epigenetic Drug Valemetostat Shows Dual Action Against HTLV-1 Eye Inflammation
A new study shows that the dual EZH1/2 inhibitor valemetostat counteracts HTLV-1-induced epigenetic changes in retinal cells and suppresses viral ...
Two Trypanosome Species, Same Parasite Burden, Very Different Fates in Mice
A controlled mouse study shows that Trypanosoma congolense and Trypanosoma brucei produce similar parasite burdens and organ damage but sharply ...
Tiny Blood-Borne Vesicles Carry Cytokine Clues to ER-Positive Breast Cancer and Its Treatment Response
Norwegian researchers report that cytokines carried on blood-borne extracellular vesicles distinguish ER-positive breast cancer patients from healthy individuals and shift ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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