Estrogen Shields Females From Severe Hepatitis A, Mouse Study Finds
A mouse study shows that male sex hormones' absence and female estrogen signaling shape hepatitis A virus replication and liver ...
Tag: Hepatocytes
CRISPR Screen Maps the Hidden Control Network of the Body’s Pollution-Sensing Receptor
A genome-scale CRISPR screen in human hepatocytes has revealed an extensive network of regulators governing the aryl hydrocarbon receptor, including ...
Copper Overload Silences a Key Liver Fat Gene, Pushing Cells Into Ferroptosis in Wilson Disease
New research shows that copper accumulation in Wilson disease shuts down the PPARα–FABP1 fat-handling axis in hepatocytes, sensitizing them to ...
Every Liver Cell Counted: Whole-Organ Microscopy Reveals How Organs Grow
A new whole-organ expansion microscopy technique has counted every hepatocyte in the adult zebrafish liver, revealing a 538-fold growth burst ...
Microplastics Overwhelm Liver Immune Cells and Derail Metabolism in Mice
A twelve-week mouse study shows that microplastics and nanoplastics accumulate in liver macrophages and disrupt metabolism in strikingly different ways ...
Simple Rocking Trick Lets Labs Dial Liver Spheroid Size Up or Down
Researchers show that adjusting rocker speed and cell seeding density predictably tunes hepatic spheroid size while preserving liver cell metabolic ...
Ubiquitin Enzyme UBE2N Emerges as Master Switch Between Liver Repair and Damage
A new Nature Metabolism study identifies the ubiquitin-conjugating enzyme UBE2N as the molecular switch that determines whether hepatocytes undergo protective ...
Exploring the Dual Role of Senescence in Liver Disease: Insights and Emerging Therapies from the Chinese Medical Journal
Cellular senescence represents a fundamental biological phenomenon characterized by the irreversible arrest of the cell cycle, a process initiated in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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