PI3K/AKT/mTOR Pathway Emerges as Central Target in Gastrointestinal Cancers
A comprehensive review finds that the PI3K/AKT/mTOR signaling axis drives progression and therapy resistance in gastrointestinal cancers, but clinical success ...
Tag: hepatocellular carcinoma
Stronger Chemo Dose Fails to Extend Survival in Liver Cancer Embolization Study
A retrospective Australian cohort study found that a more than twelvefold increase in doxorubicin concentration during conventional transarterial chemoembolization produced ...
New spatial metabolomics method maps hidden metabolic regions inside liver tumors
A new spatially guided metabolomics approach maps overlapping metabolic regions in liver tumors and reveals that over half of bulk-detected ...
AI Learns to Trace Liver Tumors on CT Scans with New Attention-Powered Network
A new U-shaped deep learning network with an attention fusion module outperforms established models in segmenting the liver and its ...
Organoid Platform Uncovers mITGB2 as a Promising CD4-Targeting Neoantigen in Liver Cancer
Using patient-derived hepatocellular carcinoma organoids, researchers identified mITGB2, a splice-variant-derived peptide presented by MHC class II, as a functionally immunogenic ...
Mushroom Compound Pachymic Acid Supercharges Lenvatinib Against Liver Cancer by Starving Tumors of Sugar
A new study shows that pachymic acid, a compound from the medicinal mushroom Poria cocos, synergizes with lenvatinib against hepatocellular ...
How Immunotherapy Is Rewriting the Rules of Liver Cancer Treatment
A sweeping review details how immune checkpoint inhibitors, combination regimens, CAR-T cells, vaccines, and oncolytic viruses are transforming treatment of ...
Prostate Cancer Tracer Lights Up Liver Cancer Blood Vessels in Landmark Imaging Study
A prospective Italian study shows that gallium-68 PSMA-11 PET/CT uptake in hepatocellular carcinoma correlates with PSMA expression in tumor-associated blood ...
Liquid Embolic Turns Liver Cancer Emergencies into Curable Cases
A low-viscosity EVOH liquid embolic used to stop bleeding from ruptured liver tumors achieved rapid hemostasis and shrank the cancers ...
Awake Liver Cancer Radiation: Brachytherapy Without General Anesthesia Proves Safe
A prospective study of 74 patients shows CT-guided high-dose-rate brachytherapy for liver tumors can be performed safely and with minimal ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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