Activated Protein C Keeps Blood Stem Cells Resting and Boosts Transplant Success
University of Zurich researchers found that a one-hour treatment with activated protein C keeps human blood stem cells in a ...
Tag: hematopoiesis
Binary Trees for Cell Fates: New Algorithm Reshapes Single-Cell Trajectory Inference
Researchers in Hong Kong and Japan have developed an integer programming method that constrains single-cell trajectory trees to binary branching, ...
Single Transcription Factor PU.1 Rapidly Converts Fibroblasts into Macrophage-Lineage Cells
Researchers at Mie University show that the transcription factor PU.1 alone can rapidly reprogram fibroblasts into transplantable macrophage-lineage cells, bypassing ...
Starvation Can Mimic Bone Cancer: Malnutrition-Driven Marrow Lesions Reverse with Recovery
A Japanese case report shows that severe malnutrition can produce tumor-like bone marrow lesions that fully reverse with nutritional recovery.
Interferon-α Rewrites Clonal Competition in Human Blood Development
Single-cell multiomics of blood stem cells from myeloproliferative neoplasm patients shows that interferon-α normalizes blood counts by boosting lymphoid differentiation ...
Cytotoxic CD4+ T cells drive aging-related myelopoiesis through CCL5–CCR5 signaling
A new Nature Aging study shows that cytotoxic CD4+ T cells accumulating in aged bone marrow drive myeloid-biased blood production ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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