Tag: granulosa cells

A narrative review finds that extracellular vesicles from several cell sources affect ovarian, metabolic and oocyte-related endpoints in PMOS models, ...

A new study links declining methylation of the ESR2 promoter to rising gene expression in sheep ovaries as puberty begins, ...

Activating the nuclear receptor PPARγ with rosiglitazone raised AMH signaling and improved follicle numbers, oocyte quality, and blastocyst development in ...

New research in Nature Metabolism reveals that the metabolic enzyme NNMT drives hyperandrogenism in polyendocrine metabolic ovarian syndrome by depleting ...

A critical review finds strong mechanistic and animal evidence for a gut–ovarian axis but no completed human trial showing that ...

A new rat study shows the chemotherapy drug cyclophosphamide accelerates ovarian aging by depleting riboflavin kinase, destabilizing FAD-dependent cryptochrome clock ...

A lineage-tracing study in mice shows that oocytes activated early in life can persist for nearly the entire reproductive lifespan ...

New research shows that the natural polyamine spermidine protects pig ovarian granulosa cells from copper overload-induced cuproptosis by suppressing miR-194a-5p ...

A new mouse and cell study identifies Ywhab as a candidate downstream target of the oocyte transcription factor Figla during ...

Researchers have engineered fully human, follicle-mimetic ovarian spheroids that drive endometrial organoid folding and secretory differentiation in ways static hormone ...