Sodium selenite curbs bone loss in mice through GPX4-linked ferroptosis inhibition
Sodium selenite reduced ferroptosis and improved bone formation through GPX4 in cell and ovariectomized mouse experiments, preclinical findings that do ...
Tag: GPX4
Astragaloside IV Emerges as a Candidate Ferroptosis Link in Heart Hypertrophy
Astragaloside IV reduces pathological cardiac hypertrophy and suppresses ferroptosis in separate models, but direct experiments are needed to establish whether ...
Turning Off a Cancer Cell’s Survival Switch: How NRF2 Controls Ferroptosis in Targeted Therapy
A new review details how the NRF2 transcription factor shields cancer cells from iron-dependent ferroptotic death and how natural and ...
Mitochondria emerge as the central hub linking cell death and metabolism in gum disease
A new review proposes that mitochondrial collapse drives a self-reinforcing cycle linking ferroptosis and metabolic reprogramming in periodontitis, opening the ...
Hidden RNA Structures in Pancreatic Cancer Cells Reveal New Drug Vulnerability
New research reveals that NEAT1-built nuclear structures called paraspeckles determine both the identity of pancreatic cancer cells and their resistance ...
How Broken Body Clocks and Iron-Driven Cell Death May Fuel Hypertension
A new review proposes that circadian disruption may lower the threshold for iron-driven ferroptotic cell death in blood vessels and ...
Two Cell Death Pathways May Converge to Drive Deadly Intestinal Disease in Preterm Infants
A new review argues that ferroptosis and pyroptosis may converge to drive necrotizing enterocolitis in preterm infants, and that biomarker-guided ...
Plant Compound Acteoside Shields Retinal Cells From Sugar-Driven Ferroptosis by Switching On NRF2
New research shows the plant compound acteoside protects retinal pigment epithelial cells and diabetic mouse retinae from iron-dependent ferroptotic damage ...
Iron’s Dark Side: How Ferroptosis Drives Brain Disease and What Could Stop It
A new review proposes the Iron-Brain Nexus framework to explain why the brain is uniquely vulnerable to iron-dependent ferroptotic cell ...
Stevia Extract Shields Diabetic Livers by Taming Iron-Driven Cell Death
A new rat study shows aqueous stevia extract protects diabetic livers by suppressing ferroptosis, boosting antioxidant enzymes, and reducing inflammation.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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