Cholesterol Ratio Linked to Higher Odds of Gout-Driving Uric Acid Buildup
A retrospective study of 2,699 fracture patients finds that a higher non-HDL-C/HDL-C cholesterol ratio is modestly associated with prevalent hyperuricemia, ...
Tag: gout
A Common Amino Acid Throws a Molecular Wrench Into the Body’s Inflammation Machine
New research shows the dietary amino acid l-arginine directly binds the NLRP3 inflammasome and blocks its assembly, easing inflammatory and ...
Non-Alcoholic Beer Can Hide as Much Purine as Regular Beer, Study Finds
A new HPLC-based analysis of 43 beverages shows that non-alcoholic beers can retain purine levels comparable to full-strength beer, with ...
Gut Fungi Leave a Distinct Signature in Gout, Metagenomic Study Finds
A reanalysis of 307 fecal metagenomic samples reveals that gout patients carry distinct gut fungal signatures linked to bacterial communities ...
Belly Fat and Blood Fats Drive Gout-Causing Uric Acid, But Not Equally in Men and Women
A five-year cohort study of more than 10,000 Chinese adults found that metabolic syndrome raises hyperuricemia risk in both sexes, ...
Nanozymes, Engineered Gut Bacteria and mRNA Offer New Hope Against Hyperuricemia
A sweeping review details how nanozyme cascade reactors, biomimetic delivery platforms, gut-targeted engineered probiotics, natural products, mRNA therapy and immune ...
AI Chatbots Redesign a Plant Molecule to Out-Bind a Gout Drug
Researchers used three AI platforms to structurally modify the natural compound beta-caryophyllene and computationally identified derivatives that bind xanthine oxidase ...
First-in-Human Trial Shows PEGylated Uricase HZBio1 Is Well Tolerated and Slashes Uric Acid
A first-in-human phase 1a trial in China found that single intramuscular doses of the PEGylated recombinant uricase HZBio1 were well ...
Gut Bacterium Mitsuokella jalaludinii PMC73 Emerges as Gout Therapy Candidate
Researchers have isolated a human gut bacterium, Mitsuokella jalaludinii PMC73, that lowers uric acid, suppresses NLRP3 inflammasome-driven inflammation, and showed ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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