NIH grant funds research linking metabolism and glycosylation in rare diseases
A five-year NIH award will support Greenwood Genetic Center research using zebrafish models to examine how metabolism and glycosylation jointly ...
Tag: glycosylation
Sugar Coats on Death Receptors Act as Molecular Switches Deciding Cell Fate
A new review reveals that sugar chains attached to death receptors act as molecular checkpoints that determine whether cells undergo ...
From Glycans to Mitochondria: Women Scientists Map the Frontiers of Cell Death Research
A new Frontiers in Cell Death Research Topic curated by women scientists collects five studies spanning necroptosis, death receptor glycans, ...
Simple Sugar Fucose Shows Promise as New Treatment for GLUT1 Deficiency Syndrome
A case report in the Journal of Neurology documents systemic and central nervous system hypofucosylation in a child with GLUT1 ...
Glycosylation asymmetry powers capillary gel electrophoresis to quantify bispecific Fc fusion protein purity
Researchers developed a capillary gel electrophoresis method that separates a bispecific Fc fusion protein from its homodimer impurities by exploiting ...
Inside the Cell’s Metal Highway: How Zinc, Manganese, and Iron Reach the ER and Golgi
A new review maps how zinc, manganese, and iron are transported into the ER and Golgi apparatus, revealing transporter families ...
Sand Fly Saliva Test Shows Protein Factory Choice Can Make or Break Exposure Assays
A new study shows that the cellular expression system used to produce the sand fly salivary protein SP32, particularly insect-derived ...
Prenatal Ozone Exposure Reprograms Offspring Antibodies to Heighten Allergy Risk
A new Nature Communications study shows that ozone exposure during pregnancy activates maternal immunity and alters IgG glycosylation, leaving offspring—especially ...
The Golgi Apparatus Emerges as a Hidden Driver of Alzheimer’s Disease
A new review argues that the long-overlooked Golgi apparatus, supported by human genetic, proteomic, and lipidomic evidence, may be a ...
Sugar Switch on Immune Cells Could Push Macrophages Back Into Cancer-Fighting Mode
Researchers found that blocking the enzyme ST6GAL1 reverses a sugar-linkage switch on macrophages, restoring tumor-fighting behavior and slowing colorectal cancer ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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