Study Finds Important Microbial Genes Do Not Have Slower Mutation Rates
A study in PLOS Biology finds that essential genes in bacteria and yeast do not mutate at lower rates than ...
Tag: Genome architecture
Great ape centromeres reveal a shared size-and-homogeneity signature
Active centromeric alpha-satellite arrays in humans and other great apes are consistently larger and more homogeneous than inactive neighbours, letting ...
Repetitive DNA Expansion Disrupts Gene Density Uniformity Across Vertebrate Chromosomes
A comparative analysis of 262 vertebrate genomes finds that recently expanded SINE retroelements are the strongest predictor of uneven gene ...
Cohesin Loops, Baciptosis, Microexons: MSK Studies Illuminate Gene Control and Immunity
New research from Memorial Sloan Kettering Cancer Center reveals how cohesin activates distant genes, identifies an immunogenic cell death called ...
AI Decodes the Hidden Grammar of the Genome’s Master Organizer CTCF
A new computational framework called DeCTCF uses AI-predicted epigenomic features to sort more than 236,000 CTCF binding sites into 20 ...
Ancient DNA Reorganization May Explain How Octopuses Grew Such Complex Brains
A University of Vienna study finds that an ancient burst of genome reorganization created 3D DNA interactions, or regulatory entanglement, ...
Folded in Two: Liver Cells Lose a Hidden X Chromosome Shape on the Road to Cancer
Researchers have discovered that the active X chromosome in liver cells adopts a liver-specific bipartite structure whose early dissolution drives ...
Recombinase-Based Genome Mapping Enables Large-Scale Structure Profiling of Prime Edits
A new protocol promises to turn the static architecture of mammalian genomes into something far more experimentally tractable. Understanding how ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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