Genetics

New York, NY (April 10, 2021) - A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and…

Preclinical research identifies CREB1 as new therapeutic target downstream of frequently mutated genesCredit: MD Anderson Cancer Center HOUSTON - Researchers at The University of Texas MD Anderson Cancer Center have discovered that…

What The Study Did: Genome analysis was performed on SARS-CoV-2 RNA from seven patients in a long-term care facility who were asymptomatic at the time of screening. Authors: Baha Abdalhamid, M.D., Ph.D., of the University of Nebraska…

Credit: Frank Curran A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages. The findings appeared online in the journal…

New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchangedCredit: Jennifer Cook-Chrysos/Whitehead Institute Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized…

Researchers from the University of Tsukuba find that nitrate-induced control of root nodule formation results from varying DNA-binding properties of specific proteins that control gene expressionCredit: University of Tsukuba Tsukuba,…

No similar link found in muscle tissue Researchers at the Obesity Research Unit of the University of Helsinki have found that obesity clearly reduces mitochondrial gene expression in fat tissue, or adipose tissue. Mitochondria are…

New York, NY (April 9, 2021) - Sets of genes associated with resistance to immunotherapy in patients with metastatic urothelial cancer of the bladder have been identified and validated by researchers at Mount Sinai. In a study published…

MSU's expertise in fish biology, genetics helping researchers rewrite evolutionary history and shape future health studiesCredit: Reprinted with permission from R.J. Vigouroux et al. Science 372:eabe7790 (2021) The network of nerves…

Credit: Ipsaro/Joshua-Tor lab, CSHL/2021 Short pieces of DNA--jumping genes--can bounce from one place to another in our genomes. When too many DNA fragments move around, cancer, infertility, and other problems can arise. Cold…

Xue Sherry Gao developing base editors to fix multitude of single mutations that cause diseaseCredit: Jeff Fitlow/Rice University HOUSTON - (April 8, 2021) - Chemical and biomolecular engineer Xue Sherry Gao of Rice University's Brown…

Credit: Purdue University photo/Rebecca McElhoe WEST LAFAYETTE, Ind. -- Scientists have been using genetics to track diseases for decades. Now, a team at Purdue University that typically tracks malaria spread in Southern and…

Scientists at the Victor Chang Cardiac Research Institute have discovered a critical new gene that it is hoped could help human hearts repair damaged heart muscle after a heart attackCredit: Victo Chang Cardiac Research Institute …

This full assembly may contain clues to ape and human divergence; certain immune, brain and heart disorders; and other biomedical questionsCredit: Kendra Hoekzema The full assembly of human chromosome 8 is reported this week in Nature.…

Mutations to Dyrk1a gene lead to brain undergrowth; an existing drug rescues the condition in newborn miceCredit: Damon Page Lab, Scripps Research JUPITER, FL -- Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems…

Scientists across Norwich Research Park institutes are part of a major integrated UK research-industry programme led by The Alan Turing Institute, seeking out the best talent in AI and data science, developing bioscience leaders and…

Credit: Photo by Duane Moser, Desert Research Institute. It's like something out of science fiction. Research led by Bigelow Laboratory for Ocean Sciences has revealed that a group of microbes, which feed off chemical reactions…

A group of researchers led by ASHBi and CiRA Assistant Professor Tsutomu Sawai explains the ethical issues regarding brain organoid research Stem cell research has allowed medicine to go places that were once science fiction. Using stem…

Credit: Copyright: FloorFour/GMI Researchers at GMI - Gregor Mendel Institute of Molecular Plant Biology of the Austrian Academy of Sciences - uncover an ingenious mechanism by which Arabidopsis safeguards the integrity of its genome. The…

Mutations in the DNA of the cell's energy 'factories' increases the chances of survival for people with bowel cancer, according to a study published today (Thursday) in Nature Metabolism. Scientists funded by Cancer Research UK have…