Genetics

In a discovery that challenges long-held dogma in biology, researchers show that mammalian cells can convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells PHILADELPHIA - Cells contain machinery that…

GRAND RAPIDS, Mich. (JUNE 10, 2021) -- Much like a supply truck crossing the countryside, the misfolded proteins that damage neurons in Alzheimer's disease travel the "roads" of the brain, sometimes stopping and sometimes re-routing to…

The authors of the journal's 10 most oft-cited 2019 papers in 2019-20 have been awarded a certificate of publishing excellence; Get free online access to these notable papers until August 31 Calcified Tissue International and…

Zebrafish model research reveals clues about molecular triggers of Parkinson's DiseaseCredit: Matsui et al., Nat Commun. 2021 Niigata, Japan - Researchers from Brain Research Institute, Niigata University, Japan may have unraveled a…

Penn scientists have developed a new method for tracing the lineage and gene expression patterns of metastatic cancer at the single-cell levelCredit: University of Pennsylvania It's often cancer's spread, not the original tumor, that…

Credit: John Innes Centre Ever since scientists discovered cells under the microscope more than 350 years ago, they have noted that each type of cell has a characteristic size. From tiny bacteria to inches-long neurons, size matters…

Study conducted on older adults with familial and genetic risk for Alzheimer's diseaseCredit: Florida Atlantic University Increasing evidence shows that physical activity and exercise training may delay or prevent the onset of…

Researchers detail another gene target that could be the crucial link to curing different cancersCredit: Chinese Medical Journal Humans have been plagued by a myriad of deadly cancers since ages. Parallelly, they have also been…

It eventually became a Nobel prize-winning revolution when researchers first engineered CRISPR as a gene editing technology for bacterial, plant, animal and human cells. The potential of the technology is great and span from curing…

Researchers from Nara Institute of Science and Technology find that plants adapt to heat stress via an epigenetic memory mechanism, where JUMONJI proteins control small heat shock genesCredit: Nobutoshi Yamaguchi Ikoma, Japan - "If you…

New technique visualizes all gene expression from a tissue sample The 30,000 or so genes making up the human genome contain the instructions vital to life. Yet each of our cells expresses only a subset of these genes in their daily…

Benign infection can potentially send medicine into plantsCredit: Gerardo Uribe/UCR Scientists are hoping the RNA of an obscure infection can one day be used like a Trojan horse to deliver life-saving treatments to citrus trees. The…

Untangling the proteins that trigger some cancerous tumors Even on a good day, DNA is constantly getting damaged. Nicks, scratches, breaks: the delicate strands that carry life's genetic code take a beating as they jumble about in the…

Salk researchers identify how tumors cause immune cells to lose their ability to fight cancer, opening new avenues for therapies LA JOLLA--(June 10, 2021) In order for cancer to grow and spread, it has to evade detection by our immune…

Credit: Sara Basse Hansen, Aarhus University Cell viability require that a variety of functions at the cell membrane are maintained properly. P-type ATPases translocate substrates across the membrane, and they have evolved into…

The largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linked to the disease. The largest study of its kind has unveiled new insights into how genes are…

Two gene variants found in African American women may explain why they are more likely to be diagnosed with triple negative breast cancer (TNBC) than white women of European ancestry, according to Weill Cornell Medicine and…

Research makes case for genetic screening in individuals with a family history of sudden death from a heart problem As many as 450,000 Americans die every year from a sudden, fatal heart condition, and in slightly more than one in ten…

For decades, physicians and dieticians have urged people to limit their intake of high fat foods, citing links to poor health outcomes and some of the leading causes of death in the U.S., such as diabetes, heart disease and cancer.…

Researchers discover an unexpected link between DNA winding and metabolism in the gut to ameliorate ageingCredit: Hanna Salmonowicz, Monney Medical Media, 2021 Our genetic material is stored in our cells in a specific way to make the…