Python Package Simplifies Complex DNA Library Design
A new Python package called PoolParty streamlines the design of DNA sequence libraries for high-throughput biological experiments by using directed ...
Tag: functional genomics
AI Model Generates Genomic Sequences Preserving Biological Structure
A new multi-task adversarial autoencoder framework generates functional genomic sequences that preserve biophysical properties and emergent biological structure, outperforming standard ...
Hidden DNA Duplication Behind a Puzzling Arabidopsis Mutant Phenotype
A hidden 137-kilobase inverted duplication linked to a T-DNA insertion, not the intended gene knockouts, explains the severe light-dependent growth ...
African-led genomics takes centre stage in global precision oncology push
A conference synthesis report in BMC Proceedings outlines African priorities for precision oncology, from genomic infrastructure and cancer registries to ...
Oral Biofilms Rely on Architecture, Not Just Which Microbes Are Present
A new review argues that oral biofilm disease is driven by spatial architecture, matrix chemistry and metabolism rather than microbial ...
Computational Predictions Fail to Match Measured Activity at Prostate Cancer Risk Variants
A re-analysis of prostate cancer reporter assay data shows computational annotations poorly predict measured regulatory activity, while ovarian risk variant ...
CRISPR snails: eyeless mutants made without a genome
Researchers generated eyeless F0 CRISPR-Cas9 pax6 mutants in the slipper limpet Crepidula fornicata using a de novo transcriptome instead of ...
New Barcoded Yeast Library Maps Gene-Drug Interactions Across 262 Strains
A new CRISPR-Cas9 barcoded library, BarMix, profiles 262 diverse yeast strains against 33 compounds and reveals 281 chemogenomic interactions.
Genomics Moves From Variant Discovery to Precision Diagnosis Across Rare and Common Disease
A sweeping editorial on a 2024–2025 research collection describes how long-read sequencing, newborn screening, population genomics, and functional studies are ...
Hybrid Machine Learning Pipeline Brings Transparency to Bacterial Selenoprotein Discovery
A new hybrid pipeline called SelCysML combines interpretable machine learning with BLAST-based validation to identify and functionally annotate bacterial selenoproteins ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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