Machine Learning Hunts Down Hidden Gene Switches Across the Fungal Tree of Life
Researchers at UC Berkeley used active learning and a model called ADhunter to discover and characterize nearly 10,000 transcriptional activator ...
Tag: functional genomics
Transposon tool maps the essential genes of diverse phages
Researchers have developed phage Tn-seq, an anti-CRISPR-based transposon sequencing method that maps essential genes across diverse phage genomes and enables ...
Mild Pepper Virus Turned Into a Powerful Gene Tool for Crop Scientists
Chinese researchers have engineered a new viral vector based on pepper mild mottle virus that enables rapid, high-efficiency gene expression ...
AI, CRISPR and Multi-Omics Converge to Reshape Antileishmanial Drug Discovery
A new review outlines how multi-omics, CRISPR functional genomics, artificial intelligence and host-directed immunotherapy can be integrated into a precision ...
CRISPRi Screens Inside Living Mice Map How E. coli Adapts to the Gut
An in vivo CRISPR interference platform reveals the diet-dependent, strain-specific and inflammation-shaped genetic adaptations that allow different Escherichia coli strains ...
Common RT–qPCR Artifact May Inflate RNA Knockdown in CRISPR Experiments
New research shows that a pervasive RT–qPCR artifact can artificially inflate reported RNA knockdown by RNA-targeting CRISPR systems.
Yeast Genetics Map How Thousands of Variants Reshape the Protein Interactome
A large-scale study in budding yeast has mapped how roughly 12,000 natural genetic variants reshape the strength of protein–protein interactions ...
New Statistical Tool Speeds Up Gene Perturbation Screening in Single Cells
Researchers at Genentech have developed Fishash, a fast Fisher's Exact Test-based method that improves the accuracy and speed of assigning ...
Eggplant genetics and biotechnology advance crops for food security
Eggplant, one of the world's most beloved vegetables and a staple of cuisines from South Asia to the Mediterranean, is ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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