Tag: functional genomics

A comparative study of mouse germ cell promoters finds the Ldhc promoter drives the strongest and most reliable transgene expression ...

Researchers have built the first efficient stable transformation system for pomegranate and used it to show that the transcription factor ...

A transcriptome-scale CRISPR-Cas13 screening platform called CaRPool-seq has identified 778 essential long non-coding RNAs in human cells, including 46 required ...

A genome-wide association study of 96 rose genotypes has identified a major chromosome 2 region controlling how efficiently Agrobacterium-delivered GFP ...

A comparative genomics study of Pseudomonas aeruginosa has identified protein clusters enriched in human clinical isolates, including twelve uncharacterized gene ...

A Genome Biology review argues that genome-wide analyses, laboratory evolution and functional screens are revealing the genetic basis of antibiotic ...

Researchers have built an inducible dCas12a-based CRISPRi/a system that dramatically expands gene regulation capabilities in the malaria parasite Plasmodium falciparum ...

A new interface called MaveMD translates large-scale variant effect experiments into calibrated clinical evidence, enabling classification of 75 percent of ...

Researchers at UC Berkeley used active learning and a model called ADhunter to discover and characterize nearly 10,000 transcriptional activator ...

Researchers have developed phage Tn-seq, an anti-CRISPR-based transposon sequencing method that maps essential genes across diverse phage genomes and enables ...