Plant-Derived Molecule KGA-1002 Strikes GRP94 to Collapse Liver Cancer’s Protein Folding Machinery
A synthetic guaianolide dimer derived from a plant sesquiterpenoid selectively covalently binds the ER chaperone GRP94 at serine 106, triggering ...
A synthetic guaianolide dimer derived from a plant sesquiterpenoid selectively covalently binds the ER chaperone GRP94 at serine 106, triggering ...
A conductive, antioxidant hydrogel loaded with stem cells and paired with electroacupuncture suppressed ferroptosis and restored motor function in mice ...
Scientists have engineered red blood cell-hitchhiking liposomes that co-deliver hemoglobin and paclitaxel to lung metastases, reversing hypoxia-driven drug resistance and ...
Researchers in Beijing have identified a PUM2-PAFAH1B1 regulatory axis that triggers ferroptosis and overcomes radioresistance to iodine-125 seed therapy in ...
A new review in Reproductive Sciences details how the metabolic disturbances of polyendocrine metabolic ovarian syndrome, the renamed polycystic ovary ...
A bio-inspired hydrogel combining baicalein, glycyrrhizic acid nanofibers, gelatin and zinc ions suppresses ferroptosis in endothelial cells and closed 96 ...
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
A glutathione-responsive nanoparticle covalently combining camptothecin and a sonosensitizer suppressed colorectal tumors in mice by 85 percent by simultaneously activating ...
New research shows the anti-HER2 antibody-drug conjugate disitamab vedotin kills breast cancer cells through ferroptosis, releasing danger signals that activate ...
New research shows the breast cancer drug lapatinib protects lung cancer cells from cysteine starvation-induced ferroptosis by restraining mitochondrial metabolic ...
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© 2025 Scienmag - Science Magazine