Scientists Link a DNA-Building Enzyme to Fat Rewiring and Chemotherapy Failure in Pancreatic Cancer
A new study identifies RRM2 as a gene that connects nucleotide metabolism and SREBP1/FASN-driven lipid remodeling to gemcitabine resistance in ...
Tag: fatty acid synthesis
Silencing a Fat-Making Master Switch Pushes Pancreatic Cancer Cells Toward Self-Destruction
New research links elevated SREBF1 expression to lipid metabolism signatures in pancreatic cancer and shows that silencing the gene triggers ...
Rice Pathogen’s Dual-Purpose Enzyme Keeps Its Membrane Intact and Its Virulence Sharp
A bifunctional enzyme in the rice blight pathogen Xanthomonas oryzae pv. oryzae doubles as a quorum-sensing signal synthase and an ...
Cancer Cells Turn Fat Factories: SOX9 Fuels Colorectal Cancer Spread Through Lipid Rewiring
New research reveals that the transcription factor SOX9 drives colorectal cancer metastasis by directly activating the fat-synthesizing enzyme FASN, and ...
Lipid Metabolism Emerges as a Central Driver of Drug Resistance in Aggressive Lymphoma
A new review argues that lipid metabolic reprogramming acts as a convergence node for treatment resistance in aggressive non-Hodgkin lymphoma, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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