Multi-omics study links kwashiorkor to tissue remodeling and lipid disruption
A matched multi-omics study of 180 children in Niger identifies extracellular matrix proteins and sphingolipid disturbances as molecular signatures of ...
Tag: extracellular matrix
Blood Proteins Linked to Heart Imaging Signatures and Disease Risk in Large UK Biobank Study
A UK Biobank study linked 681 blood proteins to cardiac MRI phenotypes and used genetic analysis to prioritize potentially causal ...
Oral Biofilms Rely on Architecture, Not Just Which Microbes Are Present
A new review argues that oral biofilm disease is driven by spatial architecture, matrix chemistry and metabolism rather than microbial ...
Muscle Cells Fuse Where Mechanical Stress Concentrates, Study Finds
Researchers at FAU show that myoblasts preferentially fuse at topological defects where mechanical stress concentrates, with the extracellular matrix retaining ...
Bovine Milk Exosomes Speed Gut Recovery in Rats After Maternal Protein Malnutrition
In a rat study, post-weaning supplementation with bovine milk exosomes restored jejunal histology after maternal protein malnutrition and up-regulated smooth ...
Intrathecal Stem Cell Therapy Reshapes CSF Proteins, Not Blood Immune Cells, in Progressive MS Trial
An integrated blood and CSF multi-omics analysis of the SMART-MS randomized trial found that intrathecal mesenchymal stem cell therapy in ...
Scientists Say Alzheimer’s Vessel Findings Lack Proof of Function
A PLOS Biology Perspective argues that molecular profiling of brain blood vessels in Alzheimer's disease has outpaced functional measurements, and ...
How Hippo, Wnt, NRG1 and Notch pathways could unlock heart regeneration
A new review synthesizes the signaling pathways, extracellular matrix cues, metabolic switches and transcription factors that govern cardiomyocyte proliferation and ...
Metabolic Protein Tags Emerge as Key Players in Disc Degeneration
A new review maps how metabolite-driven protein modifications such as lactylation, O-GlcNAcylation and succinylation may link the disc's harsh metabolic ...
Airway epithelial cells emerge as central drivers of asthma inflammation and remodeling
A new review explains how barrier disruption, alarmin release and epithelial repair programs drive asthma pathology and may offer new ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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