How a Pathogen Hijacks Nerve Signals to Break Down a Worm’s Skin
Researchers discovered that the bacterium Pseudomonas aeruginosa exploits neuronal signaling in C. elegans to impair lysosomal function and disrupt collagen ...
Tag: extracellular matrix
BRCA Carriers Show Distinct Protein Signatures in Healthy Breast Tissue, Study Finds
A Mayo Clinic-led proteomic study of nearly 5,000 proteins in nonmalignant breast tissue reveals that cancer-free BRCA1/2 mutation carriers show ...
Zinc-Dependent Enzyme From Leptospira Revealed as Collagen-Degrading Virulence Candidate
Researchers have characterised for the first time the zinc-dependent metalloprotease LIC11568 from Leptospira interrogans, showing that the enzyme degrades Type ...
Every Liver Cell Counted: Whole-Organ Microscopy Reveals How Organs Grow
A new whole-organ expansion microscopy technique has counted every hepatocyte in the adult zebrafish liver, revealing a 538-fold growth burst ...
Fibronectin found to reprogram immune cells and drive tooth regeneration
Researchers have shown that the matrix protein fibronectin reprograms macrophages in damaged dental pulp into pro-angiogenic cells, enhancing blood vessel ...
Transplant Drug Rewires Prostate Tissue in Two Distinct Phases, Rat Study Finds
A new rat study shows the immunosuppressant mycophenolate mofetil dismantles prostate stromal fibers in two timed phases, reshaping collagen, immune ...
Tumor Stiffness Fingerprinted: Rheology and 3D Spheroids Map Breast Cancer Mechanics
A new multimodal platform combines 3D tumor spheroids, rheology, and compression testing to fingerprint the viscoelastic stiffness of breast cancer ...
Blood B Cell Scars: Single-Cell Study Links Antibody Cell Chaos to Post-COVID Lung Fibrosis
Single-cell transcriptomics across multiple COVID-19 cohorts reveals that peripheral B cell dysregulation, marked by plasmablast expansion and naive B cell ...
The Hidden Architects of Colorectal Cancer: How Fibroblasts Drive Treatment Failure
A new review in Cancer Cell International details how cancer-associated fibroblasts remodel the colorectal tumor microenvironment and drive resistance to ...
Fibroblast Shield: How Osteosarcoma Builds a Wall Against the Immune System
A new review maps how cancer-associated fibroblasts exclude immune cells from osteosarcoma tumors and outlines the therapeutic strategies that could ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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