Tag: extracellular matrix

Deleting the RNA splicing factor PTBP1 in cardiac fibroblasts reshapes the profibrotic response by altering alternative splicing of key fibrosis-related ...

Researchers show that Myxococcus xanthus switches between swarming and rippling through just two mechanisms—local cellular alignment and congestion-triggered reversals.

A new review proposes a staged, evidence-bound framework combining patient-specific iPSCs, atrial microphysiological systems and nanomedicine to model and potentially ...

A new imaging mass cytometry pipeline reveals region-specific extracellular matrix environments that shape immune cell behaviour during allergic airway inflammation ...

Deleting the fish-specific actinodin genes flips collagen fiber orientation in zebrafish fins from parallel to perpendicular, reshaping the appendage into ...

A new glycoproteomic analysis shows that protein-residual N-glycosylation of extracellular matrix proteins marks a myCAF-enriched stromal state in pancreatic ductal ...

New research shows that cerebrospinal fluid TIMP2 levels rise with age and track neurodegeneration in Parkinson's disease, while TIMP2 gene ...

A new study reveals that the epigenetic enzyme DOT1L protects cartilage in osteoarthritis by boosting ITCH expression, which in turn ...

A new review argues that matrix-bound extracellular vesicles retained within the extracellular matrix form a distinct, tissue-specific signalling population with ...

A prospective Finnish study of 40 trauma patients shows that intimal hyperplasia develops within days of severe leg injury and ...