PLPP4 marks a fibroblast subset that fuels tumor growth through excess matrix deposition
Researchers identified PLPP4 as a functional marker of an ECM-enriched cancer-associated fibroblast subset that promotes tumor growth and metastasis via ...
Tag: extracellular matrix deposition
Stem Cell Screening Platform Hunts for Drugs to Halt Cardiac Fibrosis
Stanford researchers have published a protocol for a high-throughput stem cell-based screening platform that identifies potential antifibrotic compounds for cardiac ...
Practical Toolbox Enables Improved In Vitro Fibrosis Modelling
Fibrosis is one of medicine’s most persistent and difficult biological problems: a repair response that refuses to switch off. Across ...
Mitochondrial One-Carbon Metabolism Drives Fibrosis via Glycine
In a groundbreaking study that could redefine our understanding of fibrotic diseases, researchers have unveiled the pivotal role of mitochondrial ...
Key Genes and Changes in Liver Fibrosis After Cholestasis
In a groundbreaking study poised to redefine our understanding of liver fibrosis, researchers have turned their focus to the enigmatic ...
Nucleic Acid Spheres Combat Liver Sinusoid Capillarisation
In an era where the quest for effective treatments against liver fibrosis has become a paramount challenge in medical research, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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