Trojan Horse Inhibitors Slip Through Gasdermin Pores to Shut Down Pyroptosis
New research shows that gasdermin D pores formed during pyroptosis can admit selectively designed caspase inhibitors, allowing the inflammatory cell ...
Tag: ESCRT
Trypanosome ESCRT Study Reveals Novel Components and Ancient Eukaryotic Machinery
A new BMC Biology study shows that trypanosomes use a heteropentameric ESCRT-I complex and an ancient Tom1-based sorting pathway, reshaping ...
ER Domains Send a Molecular Repair Crew to Mend Damaged Lysosomes
New research shows that PI3P generated on endoplasmic reticulum microdomains recruits the ATPase DFCP1 to repair damaged lysosomal membranes.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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