Chemical Tag on mRNA Supercharges Scavenger Cells to Heal Dangerous Liver Abscesses
New research shows that the m6A-writing enzyme METTL3 speeds recovery from bacterial liver abscesses by methylating Nrf2 mRNA, which arms ...
Tag: epitranscriptomics
Chemical Tag on mRNA Emerges as Master Switch Behind Tumor Immune Evasion
A new review in the Journal of Translational Medicine details how the m6A RNA modification acts as a bidirectional switch ...
Cell cycle clock controls RNA methylation through a hidden ubiquitin code
A new Nature Chemical Biology study reveals that the ubiquitin ligase RLIM tags the m6A writer METTL14 with noncanonical K27-linked ...
Chemical Tags on RNA May Steer a Sheep’s Dramatic Black-to-White Coat Change
Integrated sequencing of RNA chemical modifications and gene expression reveals candidate m6A-tagged genes linked to the developmental shift from black ...
RNA Chemical Tag Drives Endometrial Cancer Through a DNA Repair Protein, Study Finds
New research reveals that the RNA modification reader ALYREF drives endometrial cancer progression by stabilizing XRCC6 mRNA and activating Wnt/β-catenin ...
Hidden RNA Tags May Steer Lung Cancer Growth, Treatment Response, and Survival
A sweeping review reveals how the RNA modification N6-methyladenosine orchestrates lung cancer progression, drug resistance, immunotherapy response, and survival prediction.
Chemical Tags on RNA Hold the Switch That Decides Whether Cells Die of Iron
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
An RNA Eraser Gone Rogue: ALKBH5 Emerges as a Molecular Driver of Preeclampsia
New research reveals that the RNA demethylase ALKBH5 drives preeclampsia by erasing m6A marks that stabilize FPR2 messenger RNA, disrupting ...
Nanopore Direct RNA Sequencing Faces a Benchmarking Reality Check
A new review and benchmarking study finds that computational tools for detecting RNA modifications from nanopore direct RNA sequencing data ...
RNA Chemical Tag ac4C Reveals Fibroblast Signal That Drives Colorectal Cancer Aggression
A comprehensive profiling study links the ac4C RNA modification to aggressive colorectal cancer and identifies CERCAM in cancer-associated fibroblasts as ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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