Two Master Genes That Decide Whether Blood Cells Are Born or Turn Cancerous
A new review details how the Runx1 and Gata2 transcription factors architect the epigenetic landscape of blood formation and how ...
Tag: epigenetics
Epigenetics Beyond the Clinic: A New Journal Charts the Field’s Next Frontier
The launch of the open access journal Epigenetics Communications marks a push to understand dynamic epigenetic networks, publish negative results ...
Epigenetic Clocks Stay Ticking in Brain Fluid After Bleeding Stroke
A longitudinal study of 273 stroke patients shows that DNA methylation age measured in cerebrospinal fluid remains stable after aneurysmal ...
Sperm’s Epigenetic Balancing Act: Flexibility Versus Stability in the Male Germline
A new review in Cellular and Molecular Life Sciences maps how the epigenome of the postnatal male germline balances the ...
How a Shifting Cast of Transcription Factors Rewires Androgen Signaling in the Aging Brain
New research shows that Alzheimer's disease disrupts androgen receptor signaling in the male brain by dismantling the collaborative transcription factor ...
A Methylation Signature in Brain Fluid Predicts Who Survives a Deadly Stroke
Researchers found that DNA methylation patterns in the STEAP3 iron-processing gene, measured in cerebrospinal fluid after a brain aneurysm rupture, ...
Gene Activity Comes in Bursts: Epigenetics Reshapes the Picture of Transcriptional Noise
A new review argues that transcription occurs in multi-scale bursts shaped by DNA methylation, histone variants, modifications and enhancer looping, ...
Gut Microbe Molecule Butyrate Rewrites Genes to Guard Against Gestational Diabetes
New research traces how a short-chain fatty acid from gut bacteria eases gestational diabetes by blocking an epigenetic brake on ...
Aging and Rejuvenation Converge on the Same Epigenetic Switch in Mouse Skin
Whole-genome sequencing of mouse skin shows that aging and partial reprogramming converge on PRC2 target genes, where methylation entropy rises ...
Smoking May Shorten Colorectal Cancer Survival Most in Tumors With Low LINE-1 Methylation
A prospective cohort study of 1,208 colorectal cancer patients finds that current smoking is linked to substantially worse survival only ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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