Tag: epigenetic reprogramming

Researchers identified the surface marker CLDN6 as a driver of liver metastasis in aggressive consensus molecular subtype 4 colorectal cancer ...

Researchers discover that mouse embryonic nuclei undergo a temporary phase of structural softening driven by autophagic lamin clearance to enable ...

A perspective in Discover Oncology highlights integrative frameworks to decode how cellular adaptations and microenvironment interactions drive drug resistance in ...

A scientific review details how lactate metabolism drives cancer epigenetic remodeling, influencing DNA methylation, histone lactylation, RNA modifications, and chromatin ...

A review highlights a lipid-to-epigenetic signaling axis that promotes intrinsic neuronal repair and synaptic reconstruction following ischemic stroke in murine ...

A theoretical framework published in Aging suggests that late-life functional decline accelerates through self-reinforcing systemic communication networks rather than cellular ...

A scientific review details how Fusobacterium nucleatum drives colorectal cancer progression and chemoresistance while paradoxically sensitizing select tumors to immunotherapy.

An integrative tissue analysis demonstrates that EZHIP connects cilia-associated neuro-epithelial and mesenchymal programs during the progression of aggressive posterior fossa ...

A new study shows that SMARCAL1 forms nuclear condensates that reprogram chromatin and methionine metabolism, weakening radiotherapy and immunotherapy responses.

A new review proposes that mature tumor cells can dedifferentiate into cancer stem cells, acting as a non-genetic engine of ...