DNA Methylation: The Dynamic Software of the Genome That Shapes Human Disease
A new collection of studies shows how the dynamic epigenetic mark of DNA methylation drives and predicts diseases from rheumatoid ...
Tag: epigenetic clock
RNA Splicing Factor SRSF1 Emerges as a Powerful New Regulator of Aging
A transcriptomic reprogramming screen has identified the RNA splicing factor SRSF1 as a conserved regulator of aging that rejuvenates aged ...
Diseased Kidneys Age Faster at the Cellular Level, Single-Cell Epigenome Atlas Reveals
A cross-species single-cell epigenome atlas shows that kidney disease accelerates epigenetic aging most dramatically in tubular epithelial cells, which lose ...
Blood Cells Rewound: Direct Neural Conversion Slowly Erases Epigenetic Age
Direct conversion of human blood cells into neural stem cells erases nearly all epigenetic age over a protracted fifty-day process ...
Teeth Without Pulp Can Still Reveal a Person’s Age Through DNA Methylation
Chinese researchers show that DNA methylation patterns in pulp-free teeth can estimate a person's age with a mean error of ...
Blood Tests of Ageing Face Off: Brain Scans and Epigenetic Clocks Beat Organ Clocks at Predicting Death
A 16-year Scottish cohort study finds that while proteomic organ clocks predict mortality, epigenetic, brain imaging, cognitive and lung function ...
Dogs’ Epigenetic Clocks Revealed: DNA Methylation Study Maps How Aging Reshapes the Canine Genome
A new GeroScience study of beagles reveals that canine aging proceeds through distinct, stage-specific epigenetic phases in which DNA methylation ...
Ancient Chinese Herbal Formulas Show Promise as Multi-Target Anti-Aging Therapies
A sweeping review maps classical Chinese medicine formulas onto the fourteen hallmarks of aging, revealing multi-target molecular mechanisms and clinical ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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