Designed Protein Blocks Inflammation Receptor at Its Membrane Core
Scripps Research scientists used computer-aided protein design to create a synthetic transmembrane protein that binds TLR4 inside the cell membrane ...
Tag: drug design
New Uracil-Based Compound Targets SARS-CoV-2 Enzyme Nsp15 With Promising Antiviral Activity
A newly synthesized tipiracil-inspired bromopyrimidinone shows favorable docking to the SARS-CoV-2 endoribonuclease Nsp15 and protects infected Vero E6 cells, raising ...
Chemists Craft a One-Handed Molecule That Disarms a Cell-Death Protein
Chemists have developed a single-enantiomer covalent inhibitor that locks the cell-death protein BAX in its inactive state and protects tissue ...
AI That Learns the Rules: Symbolic Neural Generators Design New Drug Candidates
Researchers have unveiled a hybrid AI framework that combines logical rule-learning with large language models to generate drug candidate molecules ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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