Gene Importance Does Not Predict Mutation Rates in Bacteria and Yeast
A multiple-parameter controlled analysis of wild-type Escherichia coli and Saccharomyces cerevisiae demonstrates that genic importance, protein levels, and replication strand ...
Tag: DNA Replication
Study Finds Important Microbial Genes Do Not Have Slower Mutation Rates
A study in PLOS Biology finds that essential genes in bacteria and yeast do not mutate at lower rates than ...
Egg White Ovotransferrin Boosts Chicken Cell Proliferation Without Animal Serum
Egg white extract containing ovotransferrin enhances the serum-free proliferation of chicken myoblasts and fibroblasts by facilitating iron uptake and DNA ...
Imaging Reveals How Helicase Interactions Direct PRIMPOL Repriming at Stalled Forks
Real-time single-molecule imaging reveals that the PRIMPOL primase restarts stalled replication forks by docking directly onto the CMG helicase to ...
Review proposes PARP1 interprets DNA lesion geometry rather than acting uniformly
A review proposes that PARP1 dynamically interprets DNA lesion geometry and chromatin context rather than operating as a uniform damage ...
Ultrasensitive Imaging Reveals Vulnerable Genomic Sites Driving Cancer Drug Sensitivity
In an experimental study using cancer cell models, researchers revealed that replication failures at a small subset of vulnerable genomic ...
E1A Protein Overcomes Oxaliplatin Resistance in Cultured Colorectal Cancer Cells
Researchers restored oxaliplatin sensitivity in resistant colorectal adenocarcinoma cells by using adenoviral E1A to force cells back into the division ...
Computational Analysis Identifies New Drug Targets for Liver Cancer
A 2026 study in the Egyptian Journal of Medical Human Genetics used transcriptomic and network biology analysis to identify druggable ...
New Wee1 function explains toxic side effects of cancer drugs
Researchers have discovered a previously unknown early cell cycle function of Wee1 that may explain the toxic side effects of ...
Cells juggle two routes to make DNA building blocks, review finds
A Nature Metabolism review examines how cells balance de novo synthesis and salvage of nucleotides across tissues, immunity and cancer.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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