Tag: DNA damage response

A new review explains how radiation-induced CCL2/CCR2 signaling recruits immunosuppressive myeloid cells and remodels the tumor microenvironment, and why combining ...

Every time a human cell divides, it must copy roughly six billion letters of DNA—a feat accomplished by molecular machines ...

DNA double-strand breaks are among the most dangerous forms of genetic damage a cell can experience. When both strands of ...

The DNA damage response (DDR) and the immune system may look like separate defense networks, but new research underscores how ...

In triple-negative breast cancer (TNBC) that carries TP53 mutations, loss of one copy of the DNA ligase I gene (LIG1) ...

In a new study published in Cell Death Discovery, researchers report that piceatannol—a natural polyphenol—may act as a “senotherapeutic,” helping ...

In a groundbreaking study poised to reshape our understanding of autoimmune diseases, researchers have unveiled a previously unrecognized mechanism by ...

The quest for precise prognostic biomarkers in cancer has led researchers to explore the multifaceted roles of the Rho GTPase-activating ...

In a monumental leap forward for genetics and cancer research, scientists at the Spanish National Cancer Research Centre (CNIO) have ...

In the ever-evolving landscape of cellular biology and cancer research, few proteins have garnered as much attention and intrigue as ...