Blood or skin? The starting cell may shape hidden DNA flaws in stem cell lines
A Stanford study using optical genome mapping on 73 early-passage induced pluripotent stem cell clones finds that fibroblast-derived lines carry ...
Tag: Disease Modeling
Scientists Set the Bar for What Counts as a Real Bone Organoid
A new review in Materials Today Bio proposes the first operational definition of a bone organoid and finds that most ...
How Organoids Became Biology’s Most Powerful Miniature Laboratories
A new Nature Protocols tutorial by Munich researchers charts the full scope of organoid technology, from intestinal miniguts and brain ...
Lab-Grown Heart Models Move Closer to Predicting Human Cardiac Disease
A comprehensive review charts how cardiac organoids and engineered heart tissues are constructed, matured and translated toward predictive human cardiovascular ...
Engineered Brain Organoids Move Toward Standardized, Translational Lab Models
A new review proposes an engineering-to-function framework linking brain organoid construction variables, vascularization strategies, and functional validation to the translational ...
Induced Pluripotent Stem Cells Reshape Drug Discovery for Alzheimer’s, Diabetes and Cancer
A new review finds that induced pluripotent stem cells have transformed drug discovery for Alzheimer's disease, diabetes, arthritis and cancer ...
Hair Follicles Mailed in a Kit Yield Stem Cells and Mini Brains
A new Nature Protocols workflow shows that keratinocytes from remotely mailed hair follicles can be reprogrammed into induced pluripotent stem ...
Engineering Proteins to Reconstruct the Gut in the Laboratory
Researchers at the Institute for Bioengineering of Catalonia (IBEC) have unveiled a groundbreaking method that revolutionizes our understanding of intestinal ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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